Results for STAT5A

General Information

Gene ID 6776
Gene Symbol STAT5A
Gene Name signal transducer and activator of transcription 5A
Gene Type protein-coding
Cytoband 17q11.2
Ensembl ID ENSG00000126561
#miR regulators 3
Omim ID 601511
Gene ontology GO:0000255: allantoin metabolic process
GO:0001553: luteinization
GO:0001779: natural killer cell differentiation
GO:0006101: citrate metabolic process
GO:0006103: 2-oxoglutarate metabolic process
GO:0006105: succinate metabolic process
GO:0006107: oxaloacetate metabolic process
GO:0006351: transcription, DNA-dependent
GO:0006357: regulation of transcription from RNA polymerase II promoter
GO:0006549: isoleucine metabolic process
GO:0006573: valine metabolic process
GO:0006600: creatine metabolic process
GO:0006631: fatty acid metabolic process
GO:0007259: JAK-STAT cascade
GO:0007565: female pregnancy
GO:0007595: lactation
GO:0018108: peptidyl-tyrosine phosphorylation
GO:0019218: regulation of steroid metabolic process
GO:0019530: taurine metabolic process
GO:0019915: lipid storage
GO:0030155: regulation of cell adhesion
GO:0030856: regulation of epithelial cell differentiation
GO:0032825: positive regulation of natural killer cell differentiation
GO:0033026: negative regulation of mast cell apoptotic process
GO:0033077: T cell differentiation in thymus
GO:0038161: prolactin signaling pathway
GO:0040014: regulation of multicellular organism growth
GO:0040018: positive regulation of multicellular organism growth
GO:0042104: positive regulation of activated T cell proliferation
GO:0043029: T cell homeostasis
GO:0045086: positive regulation of interleukin-2 biosynthetic process
GO:0045579: positive regulation of B cell differentiation
GO:0045588: positive regulation of gamma-delta T cell differentiation
GO:0045647: negative regulation of erythrocyte differentiation
GO:0045931: positive regulation of mitotic cell cycle
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0045954: positive regulation of natural killer cell mediated cytotoxicity
GO:0046449: creatinine metabolic process
GO:0046543: development of secondary female sexual characteristics
GO:0046544: development of secondary male sexual characteristics
GO:0048541: Peyer's patch development
GO:0050729: positive regulation of inflammatory response
GO:0060376: positive regulation of mast cell differentiation
GO:0060397: JAK-STAT cascade involved in growth hormone signaling pathway
GO:0060740: prostate gland epithelium morphogenesis
GO:0060742: epithelial cell differentiation involved in prostate gland development
GO:0061180: mammary gland epithelium development
GO:0070668: positive regulation of mast cell proliferation
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005515: protein binding
GO:0000979: RNA polymerase II core promoter sequence-specific DNA binding
GO:0005509: calcium ion binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0004871: signal transducer activity
KEGG pathways 4012: ErbB signaling pathway
4630: Jak-STAT signaling pathway
5200: Pathways in cancer
5220: Chronic myeloid leukemia
5221: Acute myeloid leukemia

PubMed abstracts associated with STAT5A

PMID Title Tumor Value
17471233 Sensitization of osteosarcoma cells to apoptosis by oncostatin M depends on STAT5 and p53. no no
19393247 Sennoside B inhibits PDGF receptor signaling and cell proliferation induced by PDGF-BB in human osteosarcoma cells. no no
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