General Information
Gene ID | 6776 |
---|---|
Gene Symbol | STAT5A |
Gene Name | signal transducer and activator of transcription 5A |
Gene Type | protein-coding |
Cytoband | 17q11.2 |
Ensembl ID | ENSG00000126561 |
#miR regulators | 3 |
Omim ID | 601511 |
Gene ontology |
GO:0000255: allantoin metabolic process GO:0001553: luteinization GO:0001779: natural killer cell differentiation GO:0006101: citrate metabolic process GO:0006103: 2-oxoglutarate metabolic process GO:0006105: succinate metabolic process GO:0006107: oxaloacetate metabolic process GO:0006351: transcription, DNA-dependent GO:0006357: regulation of transcription from RNA polymerase II promoter GO:0006549: isoleucine metabolic process GO:0006573: valine metabolic process GO:0006600: creatine metabolic process GO:0006631: fatty acid metabolic process GO:0007259: JAK-STAT cascade GO:0007565: female pregnancy GO:0007595: lactation GO:0018108: peptidyl-tyrosine phosphorylation GO:0019218: regulation of steroid metabolic process GO:0019530: taurine metabolic process GO:0019915: lipid storage GO:0030155: regulation of cell adhesion GO:0030856: regulation of epithelial cell differentiation GO:0032825: positive regulation of natural killer cell differentiation GO:0033026: negative regulation of mast cell apoptotic process GO:0033077: T cell differentiation in thymus GO:0038161: prolactin signaling pathway GO:0040014: regulation of multicellular organism growth GO:0040018: positive regulation of multicellular organism growth GO:0042104: positive regulation of activated T cell proliferation GO:0043029: T cell homeostasis GO:0045086: positive regulation of interleukin-2 biosynthetic process GO:0045579: positive regulation of B cell differentiation GO:0045588: positive regulation of gamma-delta T cell differentiation GO:0045647: negative regulation of erythrocyte differentiation GO:0045931: positive regulation of mitotic cell cycle GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0045954: positive regulation of natural killer cell mediated cytotoxicity GO:0046449: creatinine metabolic process GO:0046543: development of secondary female sexual characteristics GO:0046544: development of secondary male sexual characteristics GO:0048541: Peyer's patch development GO:0050729: positive regulation of inflammatory response GO:0060376: positive regulation of mast cell differentiation GO:0060397: JAK-STAT cascade involved in growth hormone signaling pathway GO:0060740: prostate gland epithelium morphogenesis GO:0060742: epithelial cell differentiation involved in prostate gland development GO:0061180: mammary gland epithelium development GO:0070668: positive regulation of mast cell proliferation GO:0005829: cytosol GO:0005634: nucleus GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0005515: protein binding GO:0000979: RNA polymerase II core promoter sequence-specific DNA binding GO:0005509: calcium ion binding GO:0003700: sequence-specific DNA binding transcription factor activity GO:0004871: signal transducer activity |
KEGG pathways |
4012: ErbB signaling pathway 4630: Jak-STAT signaling pathway 5200: Pathways in cancer 5220: Chronic myeloid leukemia 5221: Acute myeloid leukemia |
PMID | Title | Tumor | Value |
---|---|---|---|
17471233 | Sensitization of osteosarcoma cells to apoptosis by oncostatin M depends on STAT5 and p53. | no | no |
19393247 | Sennoside B inhibits PDGF receptor signaling and cell proliferation induced by PDGF-BB in human osteosarcoma cells. | no | no |
title | all | all |