General Information
Gene ID | 6794 |
---|---|
Gene Symbol | STK11 |
Gene Name | serine/threonine kinase 11 |
Gene Type | protein-coding |
Cytoband | 19p13.3 |
Ensembl ID | ENSG00000118046 |
#miR regulators | 6 |
Omim ID | 175200 260350 602216 |
Gene ontology |
GO:0001558: regulation of cell growth GO:0001894: tissue homeostasis GO:0001944: vasculature development GO:0006112: energy reserve metabolic process GO:0006468: protein phosphorylation GO:0006914: autophagy GO:0006974: response to DNA damage stimulus GO:0007050: cell cycle arrest GO:0030010: establishment of cell polarity GO:0007286: spermatid development GO:0007409: axonogenesis GO:0008285: negative regulation of cell proliferation GO:0008286: insulin receptor signaling pathway GO:0010212: response to ionizing radiation GO:0045722: positive regulation of gluconeogenesis GO:0030111: regulation of Wnt receptor signaling pathway GO:0030308: negative regulation of cell growth GO:0030511: positive regulation of transforming growth factor beta receptor signaling pathway GO:0032147: activation of protein kinase activity GO:0033762: response to glucagon stimulus GO:0033993: response to lipid GO:0042304: regulation of fatty acid biosynthetic process GO:0042593: glucose homeostasis GO:0043276: anoikis GO:0044281: small molecule metabolic process GO:0045860: positive regulation of protein kinase activity GO:0046777: protein autophosphorylation GO:0050772: positive regulation of axonogenesis GO:0051291: protein heterooligomerization GO:0051645: Golgi localization GO:0051896: regulation of protein kinase B signaling cascade GO:0060070: canonical Wnt receptor signaling pathway GO:0060770: negative regulation of epithelial cell proliferation involved in prostate gland development GO:0072332: intrinsic apoptotic signaling pathway by p53 class mediator GO:0016020: membrane GO:0005739: mitochondrion GO:0005829: cytosol GO:0005634: nucleus GO:0005737: cytoplasm GO:0043234: protein complex GO:0005515: protein binding GO:0000287: magnesium ion binding GO:0002039: p53 binding GO:0004674: protein serine/threonine kinase activity GO:0005524: ATP binding GO:0042802: identical protein binding GO:0030275: LRR domain binding GO:0030295: protein kinase activator activity GO:0032403: protein complex binding |
KEGG pathways |
4150: mTOR signaling pathway 4920: Adipocytokine signaling pathway |
PMID | Title | Tumor | Value |
---|---|---|---|
17465200 | LKB1 is crucial for TRAIL-mediated apoptosis induction in osteosarcoma. | no | no |
title | all | all |