General Information
Gene ID | 6935 |
---|---|
Gene Symbol | ZEB1 |
Gene Name | zinc finger E-box binding homeobox 1 |
Gene Type | protein-coding |
Cytoband | 10p11.2 |
Ensembl ID | ENSG00000148516 |
#miR regulators | 19 |
Omim ID | 189909 609141 613270 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0006351: transcription, DNA-dependent GO:0006357: regulation of transcription from RNA polymerase II promoter GO:0006955: immune response GO:0007389: pattern specification process GO:0008283: cell proliferation GO:0008285: negative regulation of cell proliferation GO:0010464: regulation of mesenchymal cell proliferation GO:0014823: response to activity GO:0045892: negative regulation of transcription, DNA-dependent GO:0017015: regulation of transforming growth factor beta receptor signaling pathway GO:0071230: cellular response to amino acid stimulus GO:0030857: negative regulation of epithelial cell differentiation GO:0030900: forebrain development GO:0031667: response to nutrient levels GO:0033081: regulation of T cell differentiation in thymus GO:0045666: positive regulation of neuron differentiation GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0048596: embryonic camera-type eye morphogenesis GO:0048704: embryonic skeletal system morphogenesis GO:0048752: semicircular canal morphogenesis GO:0051150: regulation of smooth muscle cell differentiation GO:0051216: cartilage development GO:0071560: cellular response to transforming growth factor beta stimulus GO:0090103: cochlea morphogenesis GO:0005634: nucleus GO:0005737: cytoplasm GO:0005667: transcription factor complex GO:0005515: protein binding GO:0003682: chromatin binding GO:0003690: double-stranded DNA binding GO:0003700: sequence-specific DNA binding transcription factor activity GO:0003713: transcription coactivator activity GO:0003714: transcription corepressor activity GO:0008134: transcription factor binding GO:0008270: zinc ion binding GO:0043565: sequence-specific DNA binding GO:0070888: E-box binding |
KEGG pathways | --- |
PMID | Title | Tumor | Value |
---|---|---|---|
22213004 | Overexpression of ZEB1 relates to metastasis and invasion in osteosarcoma. | yes | yes |
title | all | all |