Results for BUB1B

General Information

Gene ID 701
Gene Symbol BUB1B
Gene Name BUB1 mitotic checkpoint serine/threonine kinase B
Gene Type protein-coding
Cytoband 15q15
Ensembl ID ENSG00000156970
#miR regulators 4
Omim ID 114500 176430 257300 602860
Gene ontology GO:0000278: mitotic cell cycle
GO:0006915: apoptotic process
GO:0007049: cell cycle
GO:0007051: spindle organization
GO:0007067: mitosis
GO:0007091: metaphase/anaphase transition of mitotic cell cycle
GO:0007093: mitotic cell cycle checkpoint
GO:0007094: mitotic spindle assembly checkpoint
GO:0008283: cell proliferation
GO:0048015: phosphatidylinositol-mediated signaling
GO:0031145: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034501: protein localization to kinetochore
GO:0051301: cell division
GO:0051436: negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439: regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0071459: protein localization to chromosome, centromeric region
GO:0000776: kinetochore
GO:0000777: condensed chromosome kinetochore
GO:0000778: condensed nuclear chromosome kinetochore
GO:0000940: condensed chromosome outer kinetochore
GO:0005829: cytosol
GO:0005737: cytoplasm
GO:0005680: anaphase-promoting complex
GO:0005815: microtubule organizing center
GO:0048471: perinuclear region of cytoplasm
GO:0051233: spindle midzone
GO:0005515: protein binding
GO:0004672: protein kinase activity
GO:0004674: protein serine/threonine kinase activity
GO:0005524: ATP binding
KEGG pathways 4110: Cell cycle

PubMed abstracts associated with BUB1B

PMID Title Tumor Value
19778378 U2OS cells lacking Chk1 undergo aberrant mitosis and fail to activate the spindle checkpoint. no no
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