General Information
Gene ID | 7013 |
---|---|
Gene Symbol | TERF1 |
Gene Name | telomeric repeat binding factor (NIMA-interacting) 1 |
Gene Type | protein-coding |
Cytoband | 8q21.11 |
Ensembl ID | ENSG00000147601 |
#miR regulators | 4 |
Omim ID | 600951 |
Gene ontology |
GO:0000086: G2/M transition of mitotic cell cycle GO:0000723: telomere maintenance GO:0001309: age-dependent telomere shortening GO:0006919: activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0007004: telomere maintenance via telomerase GO:0007067: mitosis GO:0007094: mitotic spindle assembly checkpoint GO:0008156: negative regulation of DNA replication GO:0042493: response to drug GO:0010834: telomere maintenance via telomere shortening GO:0031116: positive regulation of microtubule polymerization GO:0032211: negative regulation of telomere maintenance via telomerase GO:0032214: negative regulation of telomere maintenance via semi-conservative replication GO:0051260: protein homooligomerization GO:0045840: positive regulation of mitosis GO:0045931: positive regulation of mitotic cell cycle GO:0051301: cell division GO:0051974: negative regulation of telomerase activity GO:0097194: execution phase of apoptosis GO:0000781: chromosome, telomeric region GO:0000783: nuclear telomere cap complex GO:0005634: nucleus GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0005819: spindle GO:0005515: protein binding GO:0003677: DNA binding GO:0003682: chromatin binding GO:0003691: double-stranded telomeric DNA binding GO:0042162: telomeric DNA binding GO:0008017: microtubule binding GO:0008301: DNA binding, bending GO:0008656: cysteine-type endopeptidase activator activity involved in apoptotic process GO:0010521: telomerase inhibitor activity GO:0042803: protein homodimerization activity GO:0046982: protein heterodimerization activity |
KEGG pathways | --- |
PMID | Title | Tumor | Value |
---|---|---|---|
19559722 | Resveratrol induces senescence-like growth inhibition of U-2 OS cells associated with the instability of telomeric DNA and upregulation of BRCA1. | no | no |
title | all | all |