Results for TERT

General Information

Gene ID 7015
Gene Symbol TERT
Gene Name telomerase reverse transcriptase
Gene Type protein-coding
Cytoband 5p15.33
Ensembl ID ENSG00000164362
#miR regulators 1
Omim ID 127550 178500 187270 601626 609135 613989 614742 615134
Gene ontology GO:0000723: telomere maintenance
GO:0007004: telomere maintenance via telomerase
GO:0022616: DNA strand elongation
GO:0032203: telomere formation via telomerase
GO:0090399: replicative senescence
GO:2001240: negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:0000781: chromosome, telomeric region
GO:0000783: nuclear telomere cap complex
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005697: telomerase holoenzyme complex
GO:0005730: nucleolus
GO:0016605: PML body
GO:0005515: protein binding
GO:0003720: telomerase activity
GO:0003721: telomeric template RNA reverse transcriptase activity
GO:0046872: metal ion binding
GO:0042162: telomeric DNA binding
GO:0042803: protein homodimerization activity
GO:0070034: telomeric RNA binding
KEGG pathways ---

PubMed abstracts associated with TERT

PMID Title Tumor Value
12943619 Telomerase, p53 and PCNA activity in osteosarcoma. yes yes
15365076 Telomerase expression predicts unfavorable outcome in osteosarcoma. yes yes
17981215 Identification of cryptic microaberrations in osteosarcoma by high-definition oligonucleotide array comparative genomic hybridization. no no
19160414 Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment. no no
19900100 Immunohistochemistry for human telomerase reverse transcriptase catalytic subunit (hTERT): a study of 143 benign and malignant soft tissue and bone tumours. yes no
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