Results for TGFA

General Information

Gene ID 7039
Gene Symbol TGFA
Gene Name transforming growth factor, alpha
Gene Type protein-coding
Cytoband 2p13
Ensembl ID ENSG00000163235
#miR regulators 10
Omim ID 190170
Gene ontology GO:0000165: MAPK cascade
GO:0000187: activation of MAPK activity
GO:0001525: angiogenesis
GO:0045741: positive regulation of epidermal growth factor-activated receptor activity
GO:0007173: epidermal growth factor receptor signaling pathway
GO:0043066: negative regulation of apoptotic process
GO:0008283: cell proliferation
GO:0042493: response to drug
GO:0042060: wound healing
GO:0045840: positive regulation of mitosis
GO:0050679: positive regulation of epithelial cell proliferation
GO:0051781: positive regulation of cell division
GO:0060749: mammary gland alveolus development
GO:0005886: plasma membrane
GO:0016021: integral to membrane
GO:0005615: extracellular space
GO:0005634: nucleus
GO:0009986: cell surface
GO:0016323: basolateral plasma membrane
GO:0031410: cytoplasmic vesicle
GO:0048471: perinuclear region of cytoplasm
GO:0005515: protein binding
GO:0001948: glycoprotein binding
GO:0004708: MAP kinase kinase activity
GO:0005154: epidermal growth factor receptor binding
GO:0008083: growth factor activity
KEGG pathways 4012: ErbB signaling pathway
5200: Pathways in cancer
5211: Renal cell carcinoma
5212: Pancreatic cancer
5214: Glioma
5215: Prostate cancer
5223: Non-small cell lung cancer

PubMed abstracts associated with TGFA

PMID Title Tumor Value
1586971 Roles of various growth factors in growth of human osteosarcoma cells which can grow in protein-free medium. no no
14669798 Biological properties and gene expression associated with metastatic potential of human osteosarcoma. no no
23631646 MicroRNA-376c inhibits cell proliferation and invasion in osteosarcoma by targeting to transforming growth factor-alpha. yes no
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