Results for TGFBR2

General Information

Gene ID 7048
Gene Symbol TGFBR2
Gene Name transforming growth factor, beta receptor II (70/80kDa)
Gene Type protein-coding
Cytoband 3p22
Ensembl ID ENSG00000163513
#miR regulators 19
Omim ID 133239 190182 610168 610380 614331
Gene ontology GO:0001568: blood vessel development
GO:0001569: patterning of blood vessels
GO:0001570: vasculogenesis
GO:0001701: in utero embryonic development
GO:0002053: positive regulation of mesenchymal cell proliferation
GO:0002088: lens development in camera-type eye
GO:0002651: positive regulation of tolerance induction to self antigen
GO:0002663: positive regulation of B cell tolerance induction
GO:0002666: positive regulation of T cell tolerance induction
GO:0006915: apoptotic process
GO:0006468: protein phosphorylation
GO:0006898: receptor-mediated endocytosis
GO:0009612: response to mechanical stimulus
GO:0007179: transforming growth factor beta receptor signaling pathway
GO:0007182: common-partner SMAD protein phosphorylation
GO:0007224: smoothened signaling pathway
GO:0007369: gastrulation
GO:0007420: brain development
GO:0007507: heart development
GO:0007566: embryo implantation
GO:0007568: aging
GO:0007584: response to nutrient
GO:0008284: positive regulation of cell proliferation
GO:0042493: response to drug
GO:0009749: response to glucose stimulus
GO:0010634: positive regulation of epithelial cell migration
GO:2000379: positive regulation of reactive oxygen species metabolic process
GO:0018105: peptidyl-serine phosphorylation
GO:0018107: peptidyl-threonine phosphorylation
GO:0030512: negative regulation of transforming growth factor beta receptor signaling pathway
GO:0031100: organ regeneration
GO:0032147: activation of protein kinase activity
GO:0035162: embryonic hemopoiesis
GO:0042060: wound healing
GO:0042127: regulation of cell proliferation
GO:0043011: myeloid dendritic cell differentiation
GO:0043415: positive regulation of skeletal muscle tissue regeneration
GO:0043627: response to estrogen stimulus
GO:0048565: digestive tract development
GO:0048661: positive regulation of smooth muscle cell proliferation
GO:0048701: embryonic cranial skeleton morphogenesis
GO:0051138: positive regulation of NK T cell differentiation
GO:0051216: cartilage development
GO:0060021: palate development
GO:0060044: negative regulation of cardiac muscle cell proliferation
GO:0060389: pathway-restricted SMAD protein phosphorylation
GO:0060434: bronchus morphogenesis
GO:0060440: trachea formation
GO:0060443: mammary gland morphogenesis
GO:0060463: lung lobe morphogenesis
GO:0070723: response to cholesterol
GO:0005886: plasma membrane
GO:0016021: integral to membrane
GO:0005829: cytosol
GO:0005901: caveola
GO:0009897: external side of plasma membrane
GO:0043235: receptor complex
GO:0070022: transforming growth factor beta receptor homodimeric complex
GO:0005515: protein binding
GO:0004675: transmembrane receptor protein serine/threonine kinase activity
GO:0004702: receptor signaling protein serine/threonine kinase activity
GO:0005024: transforming growth factor beta-activated receptor activity
GO:0005026: transforming growth factor beta receptor activity, type II
GO:0046872: metal ion binding
GO:0005524: ATP binding
GO:0005539: glycosaminoglycan binding
GO:0050431: transforming growth factor beta binding
GO:0031435: mitogen-activated protein kinase kinase kinase binding
GO:0034713: type I transforming growth factor beta receptor binding
GO:0034714: type III transforming growth factor beta receptor binding
GO:0046332: SMAD binding
KEGG pathways 4010: MAPK signaling pathway
4060: Cytokine-cytokine receptor interaction
4144: Endocytosis
4350: TGF-beta signaling pathway
4380: Osteoclast differentiation
4520: Adherens junction
5142: Chagas disease (American trypanosomiasis)
5200: Pathways in cancer
5210: Colorectal cancer
5212: Pancreatic cancer
5220: Chronic myeloid leukemia

PubMed abstracts associated with TGFBR2

PMID Title Tumor Value
23133552 Modulation of the osteosarcoma expression phenotype by microRNAs. yes no
title all all