Results for TNFRSF1A

General Information

Gene ID 7132
Gene Symbol TNFRSF1A
Gene Name tumor necrosis factor receptor superfamily, member 1A
Gene Type protein-coding
Cytoband 12p13.2
Ensembl ID ENSG00000067182
#miR regulators 4
Omim ID 142680 191190 614810
Gene ontology GO:0001666: response to hypoxia
GO:0042742: defense response to bacterium
GO:0006915: apoptotic process
GO:0006693: prostaglandin metabolic process
GO:0006954: inflammatory response
GO:0008625: extrinsic apoptotic signaling pathway via death domain receptors
GO:0009812: flavonoid metabolic process
GO:0010629: negative regulation of gene expression
GO:0016101: diterpenoid metabolic process
GO:0042981: regulation of apoptotic process
GO:0019048: modulation by virus of host morphology or physiology
GO:0019221: cytokine-mediated signaling pathway
GO:0071260: cellular response to mechanical stimulus
GO:0032496: response to lipopolysaccharide
GO:0032715: negative regulation of interleukin-6 production
GO:0032760: positive regulation of tumor necrosis factor production
GO:0033013: tetrapyrrole metabolic process
GO:0033160: positive regulation of protein import into nucleus, translocation
GO:0042511: positive regulation of tyrosine phosphorylation of Stat1 protein
GO:0043123: positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043200: response to amino acid stimulus
GO:0043279: response to alkaloid
GO:0045471: response to ethanol
GO:0045766: positive regulation of angiogenesis
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0050728: negative regulation of inflammatory response
GO:0050729: positive regulation of inflammatory response
GO:0051291: protein heterooligomerization
GO:0071392: cellular response to estradiol stimulus
GO:0097190: apoptotic signaling pathway
GO:0005886: plasma membrane
GO:0000139: Golgi membrane
GO:0005576: extracellular region
GO:0005887: integral to plasma membrane
GO:0005615: extracellular space
GO:0005634: nucleus
GO:0009986: cell surface
GO:0030424: axon
GO:0043234: protein complex
GO:0045121: membrane raft
GO:0005515: protein binding
GO:0002020: protease binding
GO:0005031: tumor necrosis factor-activated receptor activity
GO:0032403: protein complex binding
GO:0043120: tumor necrosis factor binding
KEGG pathways 4010: MAPK signaling pathway
4060: Cytokine-cytokine receptor interaction
4210: Apoptosis
4380: Osteoclast differentiation
4920: Adipocytokine signaling pathway
5010: Alzheimer's disease
5014: Amyotrophic lateral sclerosis (ALS)
5142: Chagas disease (American trypanosomiasis)
5145: Toxoplasmosis
5160: Hepatitis C

PubMed abstracts associated with TNFRSF1A

PMID Title Tumor Value
8123038 Vinblastine-dependent down-modulation of TNF receptors in human osteosarcoma cells is mediated by protein kinase C activity. no no
12926161 Serum levels of TNF-beta and sTNF-R in patients with malignant bone tumours. yes yes
14598359 Cytokine and cytokine receptor serum levels in adult bone sarcoma patients: correlations with local tumor extent and prognosis. yes yes
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