Results for TRAF2

General Information

Gene ID 7186
Gene Symbol TRAF2
Gene Name TNF receptor-associated factor 2
Gene Type protein-coding
Cytoband 9q34
Ensembl ID ENSG00000127191
#miR regulators 3
Omim ID 601895
Gene ontology GO:0002726: positive regulation of T cell cytokine production
GO:0006915: apoptotic process
GO:0007165: signal transduction
GO:0006461: protein complex assembly
GO:0006919: activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007250: activation of NF-kappaB-inducing kinase activity
GO:0042981: regulation of apoptotic process
GO:0030163: protein catabolic process
GO:0032743: positive regulation of interleukin-2 production
GO:0033209: tumor necrosis factor-mediated signaling pathway
GO:0043507: positive regulation of JUN kinase activity
GO:0043623: cellular protein complex assembly
GO:0045087: innate immune response
GO:0050870: positive regulation of T cell activation
GO:0051023: regulation of immunoglobulin secretion
GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092: positive regulation of NF-kappaB transcription factor activity
GO:0051865: protein autoubiquitination
GO:0070207: protein homotrimerization
GO:0070534: protein K63-linked ubiquitination
GO:0090073: positive regulation of protein homodimerization activity
GO:0097190: apoptotic signaling pathway
GO:2001238: positive regulation of extrinsic apoptotic signaling pathway
GO:2001239: regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:0005829: cytosol
GO:0005737: cytoplasm
GO:0009898: internal side of plasma membrane
GO:0035631: CD40 receptor complex
GO:0005515: protein binding
GO:0004842: ubiquitin-protein ligase activity
GO:0004871: signal transducer activity
GO:0005164: tumor necrosis factor receptor binding
GO:0005174: CD40 receptor binding
GO:0008270: zinc ion binding
GO:0042802: identical protein binding
GO:0019899: enzyme binding
GO:0019903: protein phosphatase binding
GO:0031625: ubiquitin protein ligase binding
GO:0031996: thioesterase binding
GO:0046625: sphingolipid binding
KEGG pathways 4010: MAPK signaling pathway
4141: Protein processing in endoplasmic reticulum
4210: Apoptosis
4380: Osteoclast differentiation
4622: RIG-I-like receptor signaling pathway
4920: Adipocytokine signaling pathway
5160: Hepatitis C
5200: Pathways in cancer
5222: Small cell lung cancer

PubMed abstracts associated with TRAF2

PMID Title Tumor Value
22068640 Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines. no no
title all all