General Information
| Gene ID | 7424 |
|---|---|
| Gene Symbol | VEGFC |
| Gene Name | vascular endothelial growth factor C |
| Gene Type | protein-coding |
| Cytoband | 4q34.3 |
| Ensembl ID | ENSG00000150630 |
| #miR regulators | 4 |
| Omim ID | 601528 |
| Gene ontology |
GO:0001525: angiogenesis GO:0002052: positive regulation of neuroblast proliferation GO:0002576: platelet degranulation GO:0007596: blood coagulation GO:0007165: signal transduction GO:0006929: substrate-dependent cell migration GO:0009887: organ morphogenesis GO:0008284: positive regulation of cell proliferation GO:0042493: response to drug GO:0016331: morphogenesis of embryonic epithelium GO:0030168: platelet activation GO:0030947: regulation of vascular endothelial growth factor receptor signaling pathway GO:0031954: positive regulation of protein autophosphorylation GO:0043536: positive regulation of blood vessel endothelial cell migration GO:0045776: negative regulation of blood pressure GO:0048010: vascular endothelial growth factor receptor signaling pathway GO:0050679: positive regulation of epithelial cell proliferation GO:0050714: positive regulation of protein secretion GO:0050918: positive chemotaxis GO:0050930: induction of positive chemotaxis GO:0051781: positive regulation of cell division GO:0060754: positive regulation of mast cell chemotaxis GO:1901492: positive regulation of lymphangiogenesis GO:0016020: membrane GO:0005576: extracellular region GO:0005615: extracellular space GO:0031093: platelet alpha granule lumen GO:0005515: protein binding GO:0008083: growth factor activity GO:0042056: chemoattractant activity GO:0043185: vascular endothelial growth factor receptor 3 binding |
| KEGG pathways |
4060: Cytokine-cytokine receptor interaction 4150: mTOR signaling pathway 4510: Focal adhesion 5200: Pathways in cancer 5211: Renal cell carcinoma 5212: Pancreatic cancer 5219: Bladder cancer |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 18438338 | VEGF-siRNA silencing induces apoptosis, inhibits proliferation and suppresses vasculogenic mimicry in osteosarcoma in vitro. | yes | no |
| title | all | all |