General Information
Gene ID | 7448 |
---|---|
Gene Symbol | VTN |
Gene Name | vitronectin |
Gene Type | protein-coding |
Cytoband | 17q11 |
Ensembl ID | ENSG00000262062 ENSG00000109072 |
#miR regulators | --- |
Omim ID | 193190 |
Gene ontology |
GO:0007155: cell adhesion GO:0006955: immune response GO:0007160: cell-matrix adhesion GO:0010811: positive regulation of cell-substrate adhesion GO:0010951: negative regulation of endopeptidase activity GO:0014911: positive regulation of smooth muscle cell migration GO:0030195: negative regulation of blood coagulation GO:0030198: extracellular matrix organization GO:0030449: regulation of complement activation GO:0030949: positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0032092: positive regulation of protein binding GO:0033627: cell adhesion mediated by integrin GO:0045087: innate immune response GO:0048260: positive regulation of receptor-mediated endocytosis GO:0050731: positive regulation of peptidyl-tyrosine phosphorylation GO:0061302: smooth muscle cell-matrix adhesion GO:0090303: positive regulation of wound healing GO:0005576: extracellular region GO:0005578: proteinaceous extracellular matrix GO:0005615: extracellular space GO:0031012: extracellular matrix GO:0071062: alphav-beta3 integrin-vitronectin complex GO:0005515: protein binding GO:0005044: scavenger receptor activity GO:0005178: integrin binding GO:0008201: heparin binding GO:0050840: extracellular matrix binding GO:0030247: polysaccharide binding |
KEGG pathways |
4510: Focal adhesion 4512: ECM-receptor interaction |
PMID | Title | Tumor | Value |
---|---|---|---|
11689005 | Inhibition of vitronectin-mediated haptotaxis and haptoinvasion of MG-63 cells by domain 5 (D5(H)) of human high-molecular-weight kininogen and identification of a minimal amino acid sequence. | no | no |
18445685 | PAI1 stimulates assembly of the fibronectin matrix in osteosarcoma cells through crosstalk between the alphavbeta5 and alpha5beta1 integrins. | yes | no |
title | all | all |