Results for VTN

General Information

Gene ID 7448
Gene Symbol VTN
Gene Name vitronectin
Gene Type protein-coding
Cytoband 17q11
Ensembl ID ENSG00000262062 ENSG00000109072
#miR regulators ---
Omim ID 193190
Gene ontology GO:0007155: cell adhesion
GO:0006955: immune response
GO:0007160: cell-matrix adhesion
GO:0010811: positive regulation of cell-substrate adhesion
GO:0010951: negative regulation of endopeptidase activity
GO:0014911: positive regulation of smooth muscle cell migration
GO:0030195: negative regulation of blood coagulation
GO:0030198: extracellular matrix organization
GO:0030449: regulation of complement activation
GO:0030949: positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032092: positive regulation of protein binding
GO:0033627: cell adhesion mediated by integrin
GO:0045087: innate immune response
GO:0048260: positive regulation of receptor-mediated endocytosis
GO:0050731: positive regulation of peptidyl-tyrosine phosphorylation
GO:0061302: smooth muscle cell-matrix adhesion
GO:0090303: positive regulation of wound healing
GO:0005576: extracellular region
GO:0005578: proteinaceous extracellular matrix
GO:0005615: extracellular space
GO:0031012: extracellular matrix
GO:0071062: alphav-beta3 integrin-vitronectin complex
GO:0005515: protein binding
GO:0005044: scavenger receptor activity
GO:0005178: integrin binding
GO:0008201: heparin binding
GO:0050840: extracellular matrix binding
GO:0030247: polysaccharide binding
KEGG pathways 4510: Focal adhesion
4512: ECM-receptor interaction

PubMed abstracts associated with VTN

PMID Title Tumor Value
11689005 Inhibition of vitronectin-mediated haptotaxis and haptoinvasion of MG-63 cells by domain 5 (D5(H)) of human high-molecular-weight kininogen and identification of a minimal amino acid sequence. no no
18445685 PAI1 stimulates assembly of the fibronectin matrix in osteosarcoma cells through crosstalk between the alphavbeta5 and alpha5beta1 integrins. yes no
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