Results for WNT10B

General Information

Gene ID 7480
Gene Symbol WNT10B
Gene Name wingless-type MMTV integration site family, member 10B
Gene Type protein-coding
Cytoband 12q13
Ensembl ID ENSG00000169884
#miR regulators 1
Omim ID 225300 601906
Gene ontology GO:0000086: G2/M transition of mitotic cell cycle
GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0002062: chondrocyte differentiation
GO:0016055: Wnt receptor signaling pathway
GO:0006629: lipid metabolic process
GO:0007050: cell cycle arrest
GO:0007224: smoothened signaling pathway
GO:0050909: sensory perception of taste
GO:0008284: positive regulation of cell proliferation
GO:0010971: positive regulation of G2/M transition of mitotic cell cycle
GO:0014835: myoblast differentiation involved in skeletal muscle regeneration
GO:0050821: protein stabilization
GO:0030182: neuron differentiation
GO:0030501: positive regulation of bone mineralization
GO:0030858: positive regulation of epithelial cell differentiation
GO:0032434: regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043065: positive regulation of apoptotic process
GO:0045165: cell fate commitment
GO:0045599: negative regulation of fat cell differentiation
GO:0045669: positive regulation of osteoblast differentiation
GO:0045899: positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0048641: regulation of skeletal muscle tissue development
GO:0048741: skeletal muscle fiber development
GO:0050680: negative regulation of epithelial cell proliferation
GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051885: positive regulation of anagen
GO:0060070: canonical Wnt receptor signaling pathway
GO:0060346: bone trabecula formation
GO:0061196: fungiform papilla development
GO:0071300: cellular response to retinoic acid
GO:0071320: cellular response to cAMP
GO:0071374: cellular response to parathyroid hormone stimulus
GO:0071425: hematopoietic stem cell proliferation
GO:0090263: positive regulation of canonical Wnt receptor signaling pathway
GO:0005576: extracellular region
GO:0005578: proteinaceous extracellular matrix
GO:0005615: extracellular space
GO:0005109: frizzled binding
GO:0048018: receptor agonist activity
KEGG pathways 4310: Wnt signaling pathway
4340: Hedgehog signaling pathway
4916: Melanogenesis
5200: Pathways in cancer
5217: Basal cell carcinoma

PubMed abstracts associated with WNT10B

PMID Title Tumor Value
18465804 Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival. yes no
23383046 FHL2 silencing reduces Wnt signaling and osteosarcoma tumorigenesis in vitro and in vivo. yes no
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