General Information
Gene ID | 7480 |
---|---|
Gene Symbol | WNT10B |
Gene Name | wingless-type MMTV integration site family, member 10B |
Gene Type | protein-coding |
Cytoband | 12q13 |
Ensembl ID | ENSG00000169884 |
#miR regulators | 1 |
Omim ID | 225300 601906 |
Gene ontology |
GO:0000086: G2/M transition of mitotic cell cycle GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0002062: chondrocyte differentiation GO:0016055: Wnt receptor signaling pathway GO:0006629: lipid metabolic process GO:0007050: cell cycle arrest GO:0007224: smoothened signaling pathway GO:0050909: sensory perception of taste GO:0008284: positive regulation of cell proliferation GO:0010971: positive regulation of G2/M transition of mitotic cell cycle GO:0014835: myoblast differentiation involved in skeletal muscle regeneration GO:0050821: protein stabilization GO:0030182: neuron differentiation GO:0030501: positive regulation of bone mineralization GO:0030858: positive regulation of epithelial cell differentiation GO:0032434: regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0043065: positive regulation of apoptotic process GO:0045165: cell fate commitment GO:0045599: negative regulation of fat cell differentiation GO:0045669: positive regulation of osteoblast differentiation GO:0045899: positive regulation of RNA polymerase II transcriptional preinitiation complex assembly GO:0048641: regulation of skeletal muscle tissue development GO:0048741: skeletal muscle fiber development GO:0050680: negative regulation of epithelial cell proliferation GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity GO:0051885: positive regulation of anagen GO:0060070: canonical Wnt receptor signaling pathway GO:0060346: bone trabecula formation GO:0061196: fungiform papilla development GO:0071300: cellular response to retinoic acid GO:0071320: cellular response to cAMP GO:0071374: cellular response to parathyroid hormone stimulus GO:0071425: hematopoietic stem cell proliferation GO:0090263: positive regulation of canonical Wnt receptor signaling pathway GO:0005576: extracellular region GO:0005578: proteinaceous extracellular matrix GO:0005615: extracellular space GO:0005109: frizzled binding GO:0048018: receptor agonist activity |
KEGG pathways |
4310: Wnt signaling pathway 4340: Hedgehog signaling pathway 4916: Melanogenesis 5200: Pathways in cancer 5217: Basal cell carcinoma |
PMID | Title | Tumor | Value |
---|---|---|---|
18465804 | Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival. | yes | no |
23383046 | FHL2 silencing reduces Wnt signaling and osteosarcoma tumorigenesis in vitro and in vivo. | yes | no |
title | all | all |