Results for WT1

General Information

Gene ID 7490
Gene Symbol WT1
Gene Name Wilms tumor 1
Gene Type protein-coding
Cytoband 11p13
Ensembl ID ENSG00000184937
#miR regulators 3
Omim ID 106210 136680 194070 194080 256370 607102 608978
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001570: vasculogenesis
GO:0001657: ureteric bud development
GO:0001658: branching involved in ureteric bud morphogenesis
GO:0001822: kidney development
GO:0003156: regulation of organ formation
GO:0006309: apoptotic DNA fragmentation
GO:0006355: regulation of transcription, DNA-dependent
GO:0006357: regulation of transcription from RNA polymerase II promoter
GO:0007281: germ cell development
GO:0007356: thorax and anterior abdomen determination
GO:0009888: tissue development
GO:0007507: heart development
GO:0007530: sex determination
GO:0043066: negative regulation of apoptotic process
GO:0008380: RNA splicing
GO:0008285: negative regulation of cell proliferation
GO:0008406: gonad development
GO:0008584: male gonad development
GO:0009451: RNA modification
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0017148: negative regulation of translation
GO:0030308: negative regulation of cell growth
GO:0030325: adrenal gland development
GO:0030539: male genitalia development
GO:0030855: epithelial cell differentiation
GO:0032835: glomerulus development
GO:0032836: glomerular basement membrane development
GO:0035802: adrenal cortex formation
GO:0043010: camera-type eye development
GO:0060231: mesenchymal to epithelial transition
GO:0060421: positive regulation of heart growth
GO:0060539: diaphragm development
GO:0060923: cardiac muscle cell fate commitment
GO:0061032: visceral serous pericardium development
GO:0071320: cellular response to cAMP
GO:0071371: cellular response to gonadotropin stimulus
GO:0072075: metanephric mesenchyme development
GO:0072112: glomerular visceral epithelial cell differentiation
GO:0072166: posterior mesonephric tubule development
GO:0072207: metanephric epithelium development
GO:0072284: metanephric S-shaped body morphogenesis
GO:0072302: negative regulation of metanephric glomerular mesangial cell proliferation
GO:2000020: positive regulation of male gonad development
GO:2000195: negative regulation of female gonad development
GO:2001076: positive regulation of metanephric ureteric bud development
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005730: nucleolus
GO:0016607: nuclear speck
GO:0005515: protein binding
GO:0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0003723: RNA binding
GO:0008270: zinc ion binding
GO:0044212: transcription regulatory region DNA binding
GO:0043565: sequence-specific DNA binding
GO:0070742: C2H2 zinc finger domain binding
KEGG pathways ---

PubMed abstracts associated with WT1

PMID Title Tumor Value
12824921 Overexpression of the Wilms' tumor gene WT1 in human bone and soft-tissue sarcomas. yes no
16547468 Immunohistochemical detection of WT1 protein in a variety of cancer cells. yes no
16857797 High WT1 expression is associated with very poor survival of patients with osteogenic sarcoma metastasis. yes yes
title all all