Results for NANOG

General Information

Gene ID 79923
Gene Symbol NANOG
Gene Name Nanog homeobox
Gene Type protein-coding
Cytoband 12p13.31
Ensembl ID ENSG00000111704
#miR regulators 2
Omim ID 607937
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001710: mesodermal cell fate commitment
GO:0001714: endodermal cell fate specification
GO:0006351: transcription, DNA-dependent
GO:0006355: regulation of transcription, DNA-dependent
GO:0009790: embryo development
GO:0009880: embryonic pattern specification
GO:0008283: cell proliferation
GO:0008284: positive regulation of cell proliferation
GO:0008406: gonad development
GO:0010454: negative regulation of cell fate commitment
GO:0010468: regulation of gene expression
GO:0017145: stem cell division
GO:0030154: cell differentiation
GO:0030514: negative regulation of BMP signaling pathway
GO:0032526: response to retinoic acid
GO:0035019: somatic stem cell maintenance
GO:0045595: regulation of cell differentiation
GO:0045931: positive regulation of mitotic cell cycle
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0005634: nucleus
GO:0005654: nucleoplasm
GO:0005730: nucleolus
GO:0001158: enhancer sequence-specific DNA binding
GO:0003677: DNA binding
GO:0003682: chromatin binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0003714: transcription corepressor activity
KEGG pathways ---

PubMed abstracts associated with NANOG

PMID Title Tumor Value
18332870 Cisplatin treatment increases survival and expansion of a highly tumorigenic side-population fraction by upregulating VEGF/Flt1 autocrine signaling. no no
19160414 Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment. no no
20309879 Prospective identification of tumorigenic osteosarcoma cancer stem cells in OS99-1 cells based on high aldehyde dehydrogenase activity. no no
20596639 Possible involvement of stem-like populations with elevated ALDH1 in sarcomas for chemotherapeutic drug resistance. no no
21178508 BMP-2 inhibits the tumorigenicity of cancer stem cells in human osteosarcoma OS99-1 cell line. no no
22870217 Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma. no no
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