General Information
Gene ID | 8029 |
---|---|
Gene Symbol | CUBN |
Gene Name | cubilin (intrinsic factor-cobalamin receptor) |
Gene Type | protein-coding |
Cytoband | 10p12.31 |
Ensembl ID | ENSG00000107611 |
#miR regulators | 14 |
Omim ID | 261100 602997 |
Gene ontology |
GO:0001894: tissue homeostasis GO:0006766: vitamin metabolic process GO:0006767: water-soluble vitamin metabolic process GO:0009235: cobalamin metabolic process GO:0006898: receptor-mediated endocytosis GO:0008202: steroid metabolic process GO:0008203: cholesterol metabolic process GO:0015889: cobalamin transport GO:0042157: lipoprotein metabolic process GO:0042359: vitamin D metabolic process GO:0042953: lipoprotein transport GO:0044281: small molecule metabolic process GO:0005886: plasma membrane GO:0016020: membrane GO:0005829: cytosol GO:0005783: endoplasmic reticulum GO:0005765: lysosomal membrane GO:0005794: Golgi apparatus GO:0030139: endocytic vesicle GO:0005905: coated pit GO:0010008: endosome membrane GO:0016324: apical plasma membrane GO:0031232: extrinsic to external side of plasma membrane GO:0031526: brush border membrane GO:0043202: lysosomal lumen GO:0005509: calcium ion binding GO:0004872: receptor activity GO:0005215: transporter activity GO:0031419: cobalamin binding GO:0042803: protein homodimerization activity |
KEGG pathways |
4977: Vitamin digestion and absorption |
PMID | Title | Tumor | Value |
---|---|---|---|
22006429 | High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes. | yes | no |
title | all | all |