General Information
| Gene ID | 81 |
|---|---|
| Gene Symbol | ACTN4 |
| Gene Name | actinin, alpha 4 |
| Gene Type | protein-coding |
| Cytoband | 19q13 |
| Ensembl ID | ENSG00000130402 |
| #miR regulators | 4 |
| Omim ID | 603278 604638 |
| Gene ontology |
GO:0001666: response to hypoxia GO:0002576: platelet degranulation GO:0051017: actin filament bundle assembly GO:0007596: blood coagulation GO:0015031: protein transport GO:0042981: regulation of apoptotic process GO:0030168: platelet activation GO:0032417: positive regulation of sodium:hydrogen antiporter activity GO:0048549: positive regulation of pinocytosis GO:0051271: negative regulation of cellular component movement GO:0051272: positive regulation of cellular component movement GO:0051764: actin crosslink formation GO:0001725: stress fiber GO:0030529: ribonucleoprotein complex GO:0005576: extracellular region GO:0005634: nucleus GO:0005737: cytoplasm GO:0030018: Z disc GO:0030863: cortical cytoskeleton GO:0031093: platelet alpha granule lumen GO:0031143: pseudopodium GO:0043234: protein complex GO:0048471: perinuclear region of cytoplasm GO:0070062: extracellular vesicular exosome GO:0005515: protein binding GO:0005509: calcium ion binding GO:0001882: nucleoside binding GO:0003779: actin binding GO:0051015: actin filament binding GO:0005178: integrin binding GO:0042803: protein homodimerization activity GO:0047485: protein N-terminus binding |
| KEGG pathways |
4510: Focal adhesion 4520: Adherens junction 4530: Tight junction 4670: Leukocyte transendothelial migration 4810: Regulation of actin cytoskeleton 5146: Amoebiasis 5322: Systemic lupus erythematosus 5412: Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 23000411 | Domain 5 of high molecular weight kininogen inhibits collagen-mediated cancer cell adhesion and invasion in association with α-actinin-4. | no | no |
| title | all | all |