Results for ACTN4

General Information

Gene ID 81
Gene Symbol ACTN4
Gene Name actinin, alpha 4
Gene Type protein-coding
Cytoband 19q13
Ensembl ID ENSG00000130402
#miR regulators 4
Omim ID 603278 604638
Gene ontology GO:0001666: response to hypoxia
GO:0002576: platelet degranulation
GO:0051017: actin filament bundle assembly
GO:0007596: blood coagulation
GO:0015031: protein transport
GO:0042981: regulation of apoptotic process
GO:0030168: platelet activation
GO:0032417: positive regulation of sodium:hydrogen antiporter activity
GO:0048549: positive regulation of pinocytosis
GO:0051271: negative regulation of cellular component movement
GO:0051272: positive regulation of cellular component movement
GO:0051764: actin crosslink formation
GO:0001725: stress fiber
GO:0030529: ribonucleoprotein complex
GO:0005576: extracellular region
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0030018: Z disc
GO:0030863: cortical cytoskeleton
GO:0031093: platelet alpha granule lumen
GO:0031143: pseudopodium
GO:0043234: protein complex
GO:0048471: perinuclear region of cytoplasm
GO:0070062: extracellular vesicular exosome
GO:0005515: protein binding
GO:0005509: calcium ion binding
GO:0001882: nucleoside binding
GO:0003779: actin binding
GO:0051015: actin filament binding
GO:0005178: integrin binding
GO:0042803: protein homodimerization activity
GO:0047485: protein N-terminus binding
KEGG pathways 4510: Focal adhesion
4520: Adherens junction
4530: Tight junction
4670: Leukocyte transendothelial migration
4810: Regulation of actin cytoskeleton
5146: Amoebiasis
5322: Systemic lupus erythematosus
5412: Arrhythmogenic right ventricular cardiomyopathy (ARVC)

PubMed abstracts associated with ACTN4

PMID Title Tumor Value
23000411 Domain 5 of high molecular weight kininogen inhibits collagen-mediated cancer cell adhesion and invasion in association with ?-actinin-4. no no
title all all