General Information
| Gene ID | 823 |
|---|---|
| Gene Symbol | CAPN1 |
| Gene Name | calpain 1, (mu/I) large subunit |
| Gene Type | protein-coding |
| Cytoband | 11q13 |
| Ensembl ID | ENSG00000014216 |
| #miR regulators | 3 |
| Omim ID | 114220 |
| Gene ontology |
GO:0006508: proteolysis GO:0008284: positive regulation of cell proliferation GO:0032801: receptor catabolic process GO:0005886: plasma membrane GO:0005737: cytoplasm GO:0005515: protein binding GO:0005509: calcium ion binding GO:0004198: calcium-dependent cysteine-type endopeptidase activity |
| KEGG pathways |
4141: Protein processing in endoplasmic reticulum 4210: Apoptosis 5010: Alzheimer's disease |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 19747555 | Silencing of calpain expression reduces the metastatic potential of human osteosarcoma cells. | no | no |
| 21573491 | Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways. | no | no |
| title | all | all |