General Information
| Gene ID | 824 |
|---|---|
| Gene Symbol | CAPN2 |
| Gene Name | calpain 2, (m/II) large subunit |
| Gene Type | protein-coding |
| Cytoband | 1q41-q42 |
| Ensembl ID | ENSG00000162909 |
| #miR regulators | 8 |
| Omim ID | 114230 |
| Gene ontology |
GO:0001666: response to hypoxia GO:0001824: blastocyst development GO:0006508: proteolysis GO:0007520: myoblast fusion GO:0016540: protein autoprocessing GO:0005886: plasma membrane GO:0000785: chromatin GO:0005634: nucleus GO:0005737: cytoplasm GO:0005515: protein binding GO:0005509: calcium ion binding GO:0004198: calcium-dependent cysteine-type endopeptidase activity GO:0008234: cysteine-type peptidase activity GO:0008092: cytoskeletal protein binding GO:0046982: protein heterodimerization activity |
| KEGG pathways |
4141: Protein processing in endoplasmic reticulum 4210: Apoptosis 4510: Focal adhesion 5010: Alzheimer's disease |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 19747555 | Silencing of calpain expression reduces the metastatic potential of human osteosarcoma cells. | no | no |
| 21573491 | Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways. | no | no |
| title | all | all |