General Information
Gene ID | 8312 |
---|---|
Gene Symbol | AXIN1 |
Gene Name | axin 1 |
Gene Type | protein-coding |
Cytoband | 16p13.3 |
Ensembl ID | ENSG00000103126 |
#miR regulators | 1 |
Omim ID | 114550 603816 607864 |
Gene ontology |
GO:0000209: protein polyubiquitination GO:0001701: in utero embryonic development GO:0001743: optic placode formation GO:0001934: positive regulation of protein phosphorylation GO:0006915: apoptotic process GO:0006913: nucleocytoplasmic transport GO:0007257: activation of JUN kinase activity GO:0007368: determination of left/right symmetry GO:0007605: sensory perception of sound GO:0008219: cell death GO:0009950: dorsal/ventral axis specification GO:0010800: positive regulation of peptidyl-threonine phosphorylation GO:0045893: positive regulation of transcription, DNA-dependent GO:0021797: forebrain anterior/posterior pattern specification GO:0021881: Wnt receptor signaling pathway involved in forebrain neuron fate commitment GO:0030163: protein catabolic process GO:0030178: negative regulation of Wnt receptor signaling pathway GO:0030511: positive regulation of transforming growth factor beta receptor signaling pathway GO:0030910: olfactory placode formation GO:0031122: cytoplasmic microtubule organization GO:0031398: positive regulation of protein ubiquitination GO:0032147: activation of protein kinase activity GO:0032436: positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0033138: positive regulation of peptidyl-serine phosphorylation GO:0034244: negative regulation of transcription elongation from RNA polymerase II promoter GO:0036342: post-anal tail morphogenesis GO:0035412: regulation of catenin import into nucleus GO:0038032: termination of G-protein coupled receptor signaling pathway GO:0051260: protein homooligomerization GO:0043547: positive regulation of GTPase activity GO:0043623: cellular protein complex assembly GO:0045599: negative regulation of fat cell differentiation GO:0045732: positive regulation of protein catabolic process GO:0046330: positive regulation of JNK cascade GO:0048048: embryonic eye morphogenesis GO:0048320: axial mesoderm formation GO:0051248: negative regulation of protein metabolic process GO:0051443: positive regulation of ubiquitin-protein ligase activity GO:0055001: muscle cell development GO:0060070: canonical Wnt receptor signaling pathway GO:0060272: embryonic skeletal joint morphogenesis GO:0060823: canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation GO:0071407: cellular response to organic cyclic compound GO:0071514: genetic imprinting GO:0090090: negative regulation of canonical Wnt receptor signaling pathway GO:0090244: Wnt receptor signaling pathway involved in somitogenesis GO:2000060: positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process GO:0005886: plasma membrane GO:0005829: cytosol GO:0005634: nucleus GO:0005737: cytoplasm GO:0005881: cytoplasmic microtubule GO:0005938: cell cortex GO:0014069: postsynaptic density GO:0016023: cytoplasmic membrane-bounded vesicle GO:0016328: lateral plasma membrane GO:0030877: beta-catenin destruction complex GO:0031410: cytoplasmic vesicle GO:0048471: perinuclear region of cytoplasm GO:0071944: cell periphery GO:0005515: protein binding GO:0002039: p53 binding GO:0004871: signal transducer activity GO:0005096: GTPase activator activity GO:0008013: beta-catenin binding GO:0008022: protein C-terminus binding GO:0042802: identical protein binding GO:0019899: enzyme binding GO:0019901: protein kinase binding GO:0031625: ubiquitin protein ligase binding GO:0032947: protein complex scaffold GO:0042803: protein homodimerization activity GO:0043621: protein self-association GO:0046332: SMAD binding GO:0070016: armadillo repeat domain binding GO:0070411: I-SMAD binding GO:0070412: R-SMAD binding |
KEGG pathways |
4310: Wnt signaling pathway 5200: Pathways in cancer 5210: Colorectal cancer 5213: Endometrial cancer 5217: Basal cell carcinoma |
PMID | Title | Tumor | Value |
---|---|---|---|
19888226 | Profiling of high-grade central osteosarcoma and its putative progenitor cells identifies tumourigenic pathways. | yes | no |
title | all | all |