Results for AXIN1

General Information

Gene ID 8312
Gene Symbol AXIN1
Gene Name axin 1
Gene Type protein-coding
Cytoband 16p13.3
Ensembl ID ENSG00000103126
#miR regulators 1
Omim ID 114550 603816 607864
Gene ontology GO:0000209: protein polyubiquitination
GO:0001701: in utero embryonic development
GO:0001743: optic placode formation
GO:0001934: positive regulation of protein phosphorylation
GO:0006915: apoptotic process
GO:0006913: nucleocytoplasmic transport
GO:0007257: activation of JUN kinase activity
GO:0007368: determination of left/right symmetry
GO:0007605: sensory perception of sound
GO:0008219: cell death
GO:0009950: dorsal/ventral axis specification
GO:0010800: positive regulation of peptidyl-threonine phosphorylation
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0021797: forebrain anterior/posterior pattern specification
GO:0021881: Wnt receptor signaling pathway involved in forebrain neuron fate commitment
GO:0030163: protein catabolic process
GO:0030178: negative regulation of Wnt receptor signaling pathway
GO:0030511: positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030910: olfactory placode formation
GO:0031122: cytoplasmic microtubule organization
GO:0031398: positive regulation of protein ubiquitination
GO:0032147: activation of protein kinase activity
GO:0032436: positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0033138: positive regulation of peptidyl-serine phosphorylation
GO:0034244: negative regulation of transcription elongation from RNA polymerase II promoter
GO:0036342: post-anal tail morphogenesis
GO:0035412: regulation of catenin import into nucleus
GO:0038032: termination of G-protein coupled receptor signaling pathway
GO:0051260: protein homooligomerization
GO:0043547: positive regulation of GTPase activity
GO:0043623: cellular protein complex assembly
GO:0045599: negative regulation of fat cell differentiation
GO:0045732: positive regulation of protein catabolic process
GO:0046330: positive regulation of JNK cascade
GO:0048048: embryonic eye morphogenesis
GO:0048320: axial mesoderm formation
GO:0051248: negative regulation of protein metabolic process
GO:0051443: positive regulation of ubiquitin-protein ligase activity
GO:0055001: muscle cell development
GO:0060070: canonical Wnt receptor signaling pathway
GO:0060272: embryonic skeletal joint morphogenesis
GO:0060823: canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation
GO:0071407: cellular response to organic cyclic compound
GO:0071514: genetic imprinting
GO:0090090: negative regulation of canonical Wnt receptor signaling pathway
GO:0090244: Wnt receptor signaling pathway involved in somitogenesis
GO:2000060: positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0005886: plasma membrane
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005881: cytoplasmic microtubule
GO:0005938: cell cortex
GO:0014069: postsynaptic density
GO:0016023: cytoplasmic membrane-bounded vesicle
GO:0016328: lateral plasma membrane
GO:0030877: beta-catenin destruction complex
GO:0031410: cytoplasmic vesicle
GO:0048471: perinuclear region of cytoplasm
GO:0071944: cell periphery
GO:0005515: protein binding
GO:0002039: p53 binding
GO:0004871: signal transducer activity
GO:0005096: GTPase activator activity
GO:0008013: beta-catenin binding
GO:0008022: protein C-terminus binding
GO:0042802: identical protein binding
GO:0019899: enzyme binding
GO:0019901: protein kinase binding
GO:0031625: ubiquitin protein ligase binding
GO:0032947: protein complex scaffold
GO:0042803: protein homodimerization activity
GO:0043621: protein self-association
GO:0046332: SMAD binding
GO:0070016: armadillo repeat domain binding
GO:0070411: I-SMAD binding
GO:0070412: R-SMAD binding
KEGG pathways 4310: Wnt signaling pathway
5200: Pathways in cancer
5210: Colorectal cancer
5213: Endometrial cancer
5217: Basal cell carcinoma

PubMed abstracts associated with AXIN1

PMID Title Tumor Value
19888226 Profiling of high-grade central osteosarcoma and its putative progenitor cells identifies tumourigenic pathways. yes no
title all all