General Information
| Gene ID | 835 |
|---|---|
| Gene Symbol | CASP2 |
| Gene Name | caspase 2, apoptosis-related cysteine peptidase |
| Gene Type | protein-coding |
| Cytoband | 7q34-q35 |
| Ensembl ID | ENSG00000106144 |
| #miR regulators | 16 |
| Omim ID | 600639 |
| Gene ontology |
GO:0001554: luteolysis GO:0003407: neural retina development GO:0006915: apoptotic process GO:0006508: proteolysis GO:0016485: protein processing GO:0006977: DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0007420: brain development GO:0007568: aging GO:0071260: cellular response to mechanical stimulus GO:0043065: positive regulation of apoptotic process GO:0043281: regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043525: positive regulation of neuron apoptotic process GO:0048011: neurotrophin TRK receptor signaling pathway GO:0097190: apoptotic signaling pathway GO:0097194: execution phase of apoptosis GO:0016020: membrane GO:0005739: mitochondrion GO:0005829: cytosol GO:0005634: nucleus GO:0005515: protein binding GO:0004197: cysteine-type endopeptidase activity GO:0019899: enzyme binding GO:0019904: protein domain specific binding |
| KEGG pathways | --- |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 18414033 | Downregulation of c-jun results in apoptosis-mediated anti-osteosarcoma activity in an orthotopic model. | no | no |
| title | all | all |