Results for CASP6

General Information

Gene ID 839
Gene Symbol CASP6
Gene Name caspase 6, apoptosis-related cysteine peptidase
Gene Type protein-coding
Cytoband 4q25
Ensembl ID ENSG00000138794
#miR regulators 2
Omim ID 601532
Gene ontology GO:0006915: apoptotic process
GO:0006508: proteolysis
GO:0006921: cellular component disassembly involved in execution phase of apoptosis
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005515: protein binding
GO:0004197: cysteine-type endopeptidase activity
GO:0008234: cysteine-type peptidase activity
KEGG pathways 4210: Apoptosis

PubMed abstracts associated with CASP6

PMID Title Tumor Value
10663637 Cisplatin (CDDP) specifically induces apoptosis via sequential activation of caspase-8, -3 and -6 in osteosarcoma. no no
17682054 Selective regulation of bone cell apoptosis by translational isoforms of the glucocorticoid receptor. no no
19488908 A caspase-6 and anti-HER2 antibody chimeric tumor-targeted proapoptotic molecule decreased metastasis of human osteosarcoma. no no
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