General Information
| Gene ID | 840 |
|---|---|
| Gene Symbol | CASP7 |
| Gene Name | caspase 7, apoptosis-related cysteine peptidase |
| Gene Type | protein-coding |
| Cytoband | 10q25 |
| Ensembl ID | ENSG00000165806 |
| #miR regulators | 23 |
| Omim ID | 601761 |
| Gene ontology |
GO:0001836: release of cytochrome c from mitochondria GO:0006915: apoptotic process GO:0006508: proteolysis GO:0016485: protein processing GO:0006921: cellular component disassembly involved in execution phase of apoptosis GO:0007507: heart development GO:0008635: activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c GO:0009411: response to UV GO:0043525: positive regulation of neuron apoptotic process GO:0097193: intrinsic apoptotic signaling pathway GO:0005829: cytosol GO:0005634: nucleus GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0005515: protein binding GO:0004197: cysteine-type endopeptidase activity GO:0004190: aspartic-type endopeptidase activity GO:0008234: cysteine-type peptidase activity |
| KEGG pathways |
4210: Apoptosis 5010: Alzheimer's disease |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 15985268 | Pigment epithelium-derived factor (PEDF)-induced apoptosis and inhibition of vascular endothelial growth factor (VEGF) expression in MG63 human osteosarcoma cells. | no | no |
| 21266106 | Depletion of Neuroguidin/CANu1 sensitizes human osteosarcoma U2OS cells to doxorubicin. | no | no |
| 21443800 | The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines. | no | no |
| 22057483 | RIP3 expression induces a death profile change in U2OS osteosarcoma cells after 5-ALA-PDT. | no | no |
| title | all | all |