Results for CASP7

General Information

Gene ID 840
Gene Symbol CASP7
Gene Name caspase 7, apoptosis-related cysteine peptidase
Gene Type protein-coding
Cytoband 10q25
Ensembl ID ENSG00000165806
#miR regulators 23
Omim ID 601761
Gene ontology GO:0001836: release of cytochrome c from mitochondria
GO:0006915: apoptotic process
GO:0006508: proteolysis
GO:0016485: protein processing
GO:0006921: cellular component disassembly involved in execution phase of apoptosis
GO:0007507: heart development
GO:0008635: activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0009411: response to UV
GO:0043525: positive regulation of neuron apoptotic process
GO:0097193: intrinsic apoptotic signaling pathway
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005515: protein binding
GO:0004197: cysteine-type endopeptidase activity
GO:0004190: aspartic-type endopeptidase activity
GO:0008234: cysteine-type peptidase activity
KEGG pathways 4210: Apoptosis
5010: Alzheimer's disease

PubMed abstracts associated with CASP7

PMID Title Tumor Value
15985268 Pigment epithelium-derived factor (PEDF)-induced apoptosis and inhibition of vascular endothelial growth factor (VEGF) expression in MG63 human osteosarcoma cells. no no
21266106 Depletion of Neuroguidin/CANu1 sensitizes human osteosarcoma U2OS cells to doxorubicin. no no
21443800 The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines. no no
22057483 RIP3 expression induces a death profile change in U2OS osteosarcoma cells after 5-ALA-PDT. no no
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