General Information
Gene ID | 8408 |
---|---|
Gene Symbol | ULK1 |
Gene Name | unc-51-like kinase 1 (C. elegans) |
Gene Type | protein-coding |
Cytoband | 12q24.3 |
Ensembl ID | ENSG00000177169 |
#miR regulators | 13 |
Omim ID | 603168 |
Gene ontology |
GO:0000045: autophagic vacuole assembly GO:0008104: protein localization GO:0006468: protein phosphorylation GO:0007265: Ras protein signal transduction GO:0010506: regulation of autophagy GO:0010508: positive regulation of autophagy GO:0016239: positive regulation of macroautophagy GO:0021707: cerebellar granule cell differentiation GO:0021933: radial glia guided migration of cerebellar granule cell GO:0031102: neuron projection regeneration GO:0031175: neuron projection development GO:0031623: receptor internalization GO:0031669: cellular response to nutrient levels GO:0042594: response to starvation GO:0046777: protein autophosphorylation GO:0048671: negative regulation of collateral sprouting GO:0048675: axon extension GO:0051386: regulation of neurotrophin TRK receptor signaling pathway GO:0005829: cytosol GO:0005737: cytoplasm GO:0005776: autophagic vacuole GO:0043005: neuron projection GO:0030659: cytoplasmic vesicle membrane GO:0034045: pre-autophagosomal structure membrane GO:0043025: neuronal cell body GO:0070969: ULK1-ATG13-FIP200 complex GO:0005515: protein binding GO:0004674: protein serine/threonine kinase activity GO:0005524: ATP binding GO:0017137: Rab GTPase binding GO:0019901: protein kinase binding GO:0032403: protein complex binding |
KEGG pathways |
4140: Regulation of autophagy 4150: mTOR signaling pathway |
PMID | Title | Tumor | Value |
---|---|---|---|
22102692 | HMGB1 promotes drug resistance in osteosarcoma. | no | no |
22301993 | Targeting HMGB1-mediated autophagy as a novel therapeutic strategy for osteosarcoma. | no | no |
title | all | all |