Results for IKBKG

General Information

Gene ID 8517
Gene Symbol IKBKG
Gene Name inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Gene Type protein-coding
Cytoband Xq28
Ensembl ID ENSG00000073009 ENSG00000269335
#miR regulators 6
Omim ID 300248 300291 300301 300584 300636 300640 308300
Gene ontology GO:0000187: activation of MAPK activity
GO:0001782: B cell homeostasis
GO:0002224: toll-like receptor signaling pathway
GO:0002755: MyD88-dependent toll-like receptor signaling pathway
GO:0002756: MyD88-independent toll-like receptor signaling pathway
GO:0009615: response to virus
GO:0006351: transcription, DNA-dependent
GO:0006954: inflammatory response
GO:0006955: immune response
GO:0006974: response to DNA damage stimulus
GO:0007249: I-kappaB kinase/NF-kappaB cascade
GO:0007250: activation of NF-kappaB-inducing kinase activity
GO:0007254: JNK cascade
GO:0019048: modulation by virus of host morphology or physiology
GO:0050852: T cell receptor signaling pathway
GO:0032481: positive regulation of type I interferon production
GO:0034134: toll-like receptor 2 signaling pathway
GO:0034138: toll-like receptor 3 signaling pathway
GO:0034142: toll-like receptor 4 signaling pathway
GO:0034146: toll-like receptor 5 signaling pathway
GO:0034162: toll-like receptor 9 signaling pathway
GO:0034166: toll-like receptor 10 signaling pathway
GO:0035666: TRIF-dependent toll-like receptor signaling pathway
GO:0035872: nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0038095: Fc-epsilon receptor signaling pathway
GO:0038123: toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124: toll-like receptor TLR6:TLR2 signaling pathway
GO:0043123: positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045087: innate immune response
GO:0051092: positive regulation of NF-kappaB transcription factor activity
GO:0051403: stress-activated MAPK cascade
GO:0070423: nucleotide-binding oligomerization domain containing signaling pathway
GO:0005622: intracellular
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0008385: IkappaB kinase complex
GO:0044444: cytoplasmic part
GO:0005515: protein binding
GO:0004871: signal transducer activity
GO:0046872: metal ion binding
GO:0019904: protein domain specific binding
GO:0046982: protein heterodimerization activity
KEGG pathways 4010: MAPK signaling pathway
4062: Chemokine signaling pathway
4210: Apoptosis
4380: Osteoclast differentiation
4620: Toll-like receptor signaling pathway
4621: NOD-like receptor signaling pathway
4622: RIG-I-like receptor signaling pathway
4623: Cytosolic DNA-sensing pathway
4660: T cell receptor signaling pathway
4662: B cell receptor signaling pathway
4920: Adipocytokine signaling pathway
5120: Epithelial cell signaling in Helicobacter pylori infection
5131: Shigellosis
5142: Chagas disease (American trypanosomiasis)
5145: Toxoplasmosis
5160: Hepatitis C
5200: Pathways in cancer
5212: Pancreatic cancer
5215: Prostate cancer
5220: Chronic myeloid leukemia
5221: Acute myeloid leukemia
5222: Small cell lung cancer
5340: Primary immunodeficiency

PubMed abstracts associated with IKBKG

PMID Title Tumor Value
20368414 IKK{gamma} protein is a target of BAG3 regulatory activity in human tumor growth. no no
title all all