General Information
Gene ID | 8533 |
---|---|
Gene Symbol | COPS3 |
Gene Name | COP9 signalosome subunit 3 |
Gene Type | protein-coding |
Cytoband | 17p11.2 |
Ensembl ID | ENSG00000141030 |
#miR regulators | 3 |
Omim ID | 604665 |
Gene ontology |
GO:0001701: in utero embryonic development GO:0007165: signal transduction GO:0009416: response to light stimulus GO:0010388: cullin deneddylation GO:0005634: nucleus GO:0005737: cytoplasm GO:0008180: COP9 signalosome GO:0005515: protein binding |
KEGG pathways | --- |
PMID | Title | Tumor | Value |
---|---|---|---|
12917637 | Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation. | yes | no |
15193436 | Overexpression through amplification of genes in chromosome region 17p11.2 approximately p12 in high-grade osteosarcoma. | yes | no |
15325100 | Amplification and overexpression of genes in 17p11.2 ~ p12 in osteosarcoma. | yes | no |
16596382 | Monoallelic deletion of the p53 gene through chromosomal translocation in a small cell osteosarcoma. | yes | no |
17366602 | COPS3 amplification and clinical outcome in osteosarcoma. | yes | yes |
21436869 | RNAi-mediated COPS3 gene silencing inhibits metastasis of osteogenic sarcoma cells. | yes | no |
22292074 | Identification of novel candidate oncogenes in chromosome region 17p11.2-p12 in human osteosarcoma. | yes | no |
title | all | all |