Results for COPS3

General Information

Gene ID 8533
Gene Symbol COPS3
Gene Name COP9 signalosome subunit 3
Gene Type protein-coding
Cytoband 17p11.2
Ensembl ID ENSG00000141030
#miR regulators 3
Omim ID 604665
Gene ontology GO:0001701: in utero embryonic development
GO:0007165: signal transduction
GO:0009416: response to light stimulus
GO:0010388: cullin deneddylation
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0008180: COP9 signalosome
GO:0005515: protein binding
KEGG pathways ---

PubMed abstracts associated with COPS3

PMID Title Tumor Value
12917637 Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation. yes no
15193436 Overexpression through amplification of genes in chromosome region 17p11.2 approximately p12 in high-grade osteosarcoma. yes no
15325100 Amplification and overexpression of genes in 17p11.2 ~ p12 in osteosarcoma. yes no
16596382 Monoallelic deletion of the p53 gene through chromosomal translocation in a small cell osteosarcoma. yes no
17366602 COPS3 amplification and clinical outcome in osteosarcoma. yes yes
21436869 RNAi-mediated COPS3 gene silencing inhibits metastasis of osteogenic sarcoma cells. yes no
22292074 Identification of novel candidate oncogenes in chromosome region 17p11.2-p12 in human osteosarcoma. yes no
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