General Information
| Gene ID | 8554 |
|---|---|
| Gene Symbol | PIAS1 |
| Gene Name | protein inhibitor of activated STAT, 1 |
| Gene Type | protein-coding |
| Cytoband | 15q |
| Ensembl ID | ENSG00000033800 |
| #miR regulators | 1 |
| Omim ID | 603566 |
| Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0006351: transcription, DNA-dependent GO:0007259: JAK-STAT cascade GO:0007283: spermatogenesis GO:0045893: positive regulation of transcription, DNA-dependent GO:0016925: protein sumoylation GO:0019221: cytokine-mediated signaling pathway GO:0030521: androgen receptor signaling pathway GO:0032436: positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0033235: positive regulation of protein sumoylation GO:0042127: regulation of cell proliferation GO:0051152: positive regulation of smooth muscle cell differentiation GO:0060333: interferon-gamma-mediated signaling pathway GO:0060334: regulation of interferon-gamma-mediated signaling pathway GO:0065004: protein-DNA complex assembly GO:0005634: nucleus GO:0005654: nucleoplasm GO:0016605: PML body GO:0016607: nuclear speck GO:0005515: protein binding GO:0003677: DNA binding GO:0003713: transcription coactivator activity GO:0003714: transcription corepressor activity GO:0008270: zinc ion binding GO:0019899: enzyme binding GO:0019789: SUMO ligase activity GO:0019904: protein domain specific binding GO:0031625: ubiquitin protein ligase binding GO:0050681: androgen receptor binding |
| KEGG pathways |
4120: Ubiquitin mediated proteolysis 4630: Jak-STAT signaling pathway 5160: Hepatitis C 5200: Pathways in cancer 5222: Small cell lung cancer |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 11451946 | Induction of apoptosis by protein inhibitor of activated Stat1 through c-Jun NH2-terminal kinase activation. | no | no |
| title | all | all |