Results for PIAS1

General Information

Gene ID 8554
Gene Symbol PIAS1
Gene Name protein inhibitor of activated STAT, 1
Gene Type protein-coding
Cytoband 15q
Ensembl ID ENSG00000033800
#miR regulators 1
Omim ID 603566
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0006351: transcription, DNA-dependent
GO:0007259: JAK-STAT cascade
GO:0007283: spermatogenesis
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0016925: protein sumoylation
GO:0019221: cytokine-mediated signaling pathway
GO:0030521: androgen receptor signaling pathway
GO:0032436: positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0033235: positive regulation of protein sumoylation
GO:0042127: regulation of cell proliferation
GO:0051152: positive regulation of smooth muscle cell differentiation
GO:0060333: interferon-gamma-mediated signaling pathway
GO:0060334: regulation of interferon-gamma-mediated signaling pathway
GO:0065004: protein-DNA complex assembly
GO:0005634: nucleus
GO:0005654: nucleoplasm
GO:0016605: PML body
GO:0016607: nuclear speck
GO:0005515: protein binding
GO:0003677: DNA binding
GO:0003713: transcription coactivator activity
GO:0003714: transcription corepressor activity
GO:0008270: zinc ion binding
GO:0019899: enzyme binding
GO:0019789: SUMO ligase activity
GO:0019904: protein domain specific binding
GO:0031625: ubiquitin protein ligase binding
GO:0050681: androgen receptor binding
KEGG pathways 4120: Ubiquitin mediated proteolysis
4630: Jak-STAT signaling pathway
5160: Hepatitis C
5200: Pathways in cancer
5222: Small cell lung cancer

PubMed abstracts associated with PIAS1

PMID Title Tumor Value
11451946 Induction of apoptosis by protein inhibitor of activated Stat1 through c-Jun NH2-terminal kinase activation. no no
title all all