General Information
Gene ID | 857 |
---|---|
Gene Symbol | CAV1 |
Gene Name | caveolin 1, caveolae protein, 22kDa |
Gene Type | protein-coding |
Cytoband | 7q31.1 |
Ensembl ID | ENSG00000105974 |
#miR regulators | 8 |
Omim ID | 601047 612526 615343 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0000165: MAPK cascade GO:0000188: inactivation of MAPK activity GO:0001525: angiogenesis GO:0001570: vasculogenesis GO:0001666: response to hypoxia GO:0001937: negative regulation of endothelial cell proliferation GO:0001960: negative regulation of cytokine-mediated signaling pathway GO:0002931: response to ischemia GO:0003057: regulation of the force of heart contraction by chemical signal GO:0007596: blood coagulation GO:0008104: protein localization GO:0006641: triglyceride metabolic process GO:0006816: calcium ion transport GO:0006874: cellular calcium ion homeostasis GO:0006940: regulation of smooth muscle contraction GO:0007519: skeletal muscle tissue development GO:0007595: lactation GO:0009267: cellular response to starvation GO:0010524: positive regulation of calcium ion transport into cytosol GO:0016050: vesicle organization GO:0019048: modulation by virus of host morphology or physiology GO:0019217: regulation of fatty acid metabolic process GO:0019915: lipid storage GO:0030193: regulation of blood coagulation GO:0030301: cholesterol transport GO:0030514: negative regulation of BMP signaling pathway GO:0030857: negative regulation of epithelial cell differentiation GO:0030879: mammary gland development GO:0031295: T cell costimulation GO:0031397: negative regulation of protein ubiquitination GO:0032091: negative regulation of protein binding GO:0032507: maintenance of protein location in cell GO:0032570: response to progesterone stimulus GO:0033137: negative regulation of peptidyl-serine phosphorylation GO:0033138: positive regulation of peptidyl-serine phosphorylation GO:0033484: nitric oxide homeostasis GO:0042310: vasoconstriction GO:0042524: negative regulation of tyrosine phosphorylation of Stat5 protein GO:0042632: cholesterol homeostasis GO:0051260: protein homooligomerization GO:0043409: negative regulation of MAPK cascade GO:0043627: response to estrogen stimulus GO:0044281: small molecule metabolic process GO:0045019: negative regulation of nitric oxide biosynthetic process GO:0045907: positive regulation of vasoconstriction GO:0046209: nitric oxide metabolic process GO:0046426: negative regulation of JAK-STAT cascade GO:0048554: positive regulation of metalloenzyme activity GO:0050900: leukocyte migration GO:0050999: regulation of nitric-oxide synthase activity GO:0051001: negative regulation of nitric-oxide synthase activity GO:0051480: cytosolic calcium ion homeostasis GO:0051592: response to calcium ion GO:0051899: membrane depolarization GO:0052547: regulation of peptidase activity GO:0055074: calcium ion homeostasis GO:0060056: mammary gland involution GO:0070836: caveola assembly GO:0071455: cellular response to hyperoxia GO:0072584: caveolin-mediated endocytosis GO:0090090: negative regulation of canonical Wnt receptor signaling pathway GO:0090263: positive regulation of canonical Wnt receptor signaling pathway GO:0097190: apoptotic signaling pathway GO:2000286: receptor internalization involved in canonical Wnt receptor signaling pathway GO:2000811: negative regulation of anoikis GO:2001238: positive regulation of extrinsic apoptotic signaling pathway GO:2001244: positive regulation of intrinsic apoptotic signaling pathway GO:0005886: plasma membrane GO:0000139: Golgi membrane GO:0005622: intracellular GO:0002080: acrosomal membrane GO:0005783: endoplasmic reticulum GO:0005887: integral to plasma membrane GO:0005768: endosome GO:0005811: lipid particle GO:0005901: caveola GO:0005929: cilium GO:0005938: cell cortex GO:0016323: basolateral plasma membrane GO:0016324: apical plasma membrane GO:0030666: endocytic vesicle membrane GO:0031410: cytoplasmic vesicle GO:0043234: protein complex GO:0045121: membrane raft GO:0048471: perinuclear region of cytoplasm GO:0005515: protein binding GO:0005102: receptor binding GO:0005113: patched binding GO:0005198: structural molecule activity GO:0015485: cholesterol binding GO:0016504: peptidase activator activity GO:0019899: enzyme binding GO:0032947: protein complex scaffold GO:0050998: nitric-oxide synthase binding |
KEGG pathways |
4144: Endocytosis 4510: Focal adhesion 5100: Bacterial invasion of epithelial cells 5416: Viral myocarditis |
PMID | Title | Tumor | Value |
---|---|---|---|
16421247 | CD99 acts as an oncosuppressor in osteosarcoma. | no | no |
17699771 | Caveolin-1 reduces osteosarcoma metastases by inhibiting c-Src activity and met signaling. | no | yes |
title | all | all |