General Information
| Gene ID | 8678 |
|---|---|
| Gene Symbol | BECN1 |
| Gene Name | beclin 1, autophagy related |
| Gene Type | protein-coding |
| Cytoband | 17q21 |
| Ensembl ID | ENSG00000126581 |
| #miR regulators | 4 |
| Omim ID | 604378 |
| Gene ontology |
GO:0000045: autophagic vacuole assembly GO:0000910: cytokinesis GO:0001666: response to hypoxia GO:0006968: cellular defense response GO:0007040: lysosome organization GO:0043066: negative regulation of apoptotic process GO:0008285: negative regulation of cell proliferation GO:0042493: response to drug GO:0016239: positive regulation of macroautophagy GO:0019048: modulation by virus of host morphology or physiology GO:0033197: response to vitamin E GO:0048666: neuron development GO:0050435: beta-amyloid metabolic process GO:0051607: defense response to virus GO:0071275: cellular response to aluminum ion GO:0016020: membrane GO:0005634: nucleus GO:0005794: Golgi apparatus GO:0005802: trans-Golgi network GO:0016023: cytoplasmic membrane-bounded vesicle GO:0030425: dendrite GO:0043234: protein complex GO:0005515: protein binding |
| KEGG pathways |
4140: Regulation of autophagy |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 20037818 | Expression of Beclin1 in osteosarcoma and the effects of down-regulation of autophagy on the chemotherapeutic sensitivity. | yes | no |
| 22102692 | HMGB1 promotes drug resistance in osteosarcoma. | no | no |
| 22301993 | Targeting HMGB1-mediated autophagy as a novel therapeutic strategy for osteosarcoma. | no | no |
| title | all | all |