Results for HYAL2

General Information

Gene ID 8692
Gene Symbol HYAL2
Gene Name hyaluronoglucosaminidase 2
Gene Type protein-coding
Cytoband 3p21.3
Ensembl ID ENSG00000068001 ENSG00000261921
#miR regulators 1
Omim ID 603551
Gene ontology GO:0000302: response to reactive oxygen species
GO:0001822: kidney development
GO:0002244: hematopoietic progenitor cell differentiation
GO:0035810: positive regulation of urine volume
GO:0009615: response to virus
GO:0005975: carbohydrate metabolic process
GO:0006027: glycosaminoglycan catabolic process
GO:0010259: multicellular organismal aging
GO:0010764: negative regulation of fibroblast migration
GO:0046677: response to antibiotic
GO:0019064: viral entry into host cell via membrane fusion with the plasma membrane
GO:0046718: viral entry into host cell
GO:0019087: transformation of host cell by virus
GO:0030203: glycosaminoglycan metabolic process
GO:0030212: hyaluronan metabolic process
GO:0030214: hyaluronan catabolic process
GO:0030308: negative regulation of cell growth
GO:0042117: monocyte activation
GO:0042307: positive regulation of protein import into nucleus
GO:0043065: positive regulation of apoptotic process
GO:0043407: negative regulation of MAP kinase activity
GO:0044281: small molecule metabolic process
GO:0044344: cellular response to fibroblast growth factor stimulus
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048705: skeletal system morphogenesis
GO:0050729: positive regulation of inflammatory response
GO:0051216: cartilage development
GO:0051607: defense response to virus
GO:0051898: negative regulation of protein kinase B signaling cascade
GO:0060586: multicellular organismal iron ion homeostasis
GO:0061099: negative regulation of protein tyrosine kinase activity
GO:0070295: renal water absorption
GO:0071347: cellular response to interleukin-1
GO:0071356: cellular response to tumor necrosis factor
GO:0071493: cellular response to UV-B
GO:0071560: cellular response to transforming growth factor beta stimulus
GO:2000484: positive regulation of interleukin-8 secretion
GO:2000778: positive regulation of interleukin-6 secretion
GO:2001238: positive regulation of extrinsic apoptotic signaling pathway
GO:0005886: plasma membrane
GO:0000139: Golgi membrane
GO:0005764: lysosome
GO:0005829: cytosol
GO:0005783: endoplasmic reticulum
GO:0046658: anchored to plasma membrane
GO:0030139: endocytic vesicle
GO:0005902: microvillus
GO:0009986: cell surface
GO:0016023: cytoplasmic membrane-bounded vesicle
GO:0016324: apical plasma membrane
GO:0031362: anchored to external side of plasma membrane
GO:0031410: cytoplasmic vesicle
GO:0044444: cytoplasmic part
GO:0045121: membrane raft
GO:0048471: perinuclear region of cytoplasm
GO:0005515: protein binding
GO:0001618: virus receptor activity
GO:0004415: hyalurononglucosaminidase activity
GO:0005540: hyaluronic acid binding
GO:0030971: receptor tyrosine kinase binding
GO:0050431: transforming growth factor beta binding
GO:0019899: enzyme binding
GO:0030294: receptor signaling protein tyrosine kinase inhibitor activity
GO:0033906: hyaluronoglucuronidase activity
KEGG pathways 531: Glycosaminoglycan degradation
1100: Metabolic pathways

PubMed abstracts associated with HYAL2

PMID Title Tumor Value
20222016 Parathyroid hormone (PTH) peptides through the regulation of hyaluronan metabolism affect osteosarcoma cell migration. no no
title all all