General Information
Gene ID | 8841 |
---|---|
Gene Symbol | HDAC3 |
Gene Name | histone deacetylase 3 |
Gene Type | protein-coding |
Cytoband | 5q31 |
Ensembl ID | ENSG00000171720 |
#miR regulators | 2 |
Omim ID | 605166 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0006351: transcription, DNA-dependent GO:0006476: protein deacetylation GO:0007219: Notch signaling pathway GO:0007346: regulation of mitotic cell cycle GO:0043066: negative regulation of apoptotic process GO:0045892: negative regulation of transcription, DNA-dependent GO:0016568: chromatin modification GO:0032922: circadian regulation of gene expression GO:0040014: regulation of multicellular organism growth GO:0044255: cellular lipid metabolic process GO:0044281: small molecule metabolic process GO:0045786: negative regulation of cell cycle GO:0046329: negative regulation of JNK cascade GO:0048011: neurotrophin TRK receptor signaling pathway GO:0051225: spindle assembly GO:0000118: histone deacetylase complex GO:0005634: nucleus GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0005876: spindle microtubule GO:0017053: transcriptional repressor complex GO:0005515: protein binding GO:0003714: transcription corepressor activity GO:0004407: histone deacetylase activity GO:0008134: transcription factor binding GO:0019899: enzyme binding GO:0031490: chromatin DNA binding GO:0032041: NAD-dependent histone deacetylase activity (H3-K14 specific) GO:0033558: protein deacetylase activity GO:0042826: histone deacetylase binding GO:0046969: NAD-dependent histone deacetylase activity (H3-K9 specific) GO:0046970: NAD-dependent histone deacetylase activity (H4-K16 specific) GO:0097372: NAD-dependent histone deacetylase activity (H3-K18 specific) |
KEGG pathways | --- |
PMID | Title | Tumor | Value |
---|---|---|---|
17956871 | Runx2- and histone deacetylase 3-mediated repression is relieved in differentiating human osteoblast cells to allow high bone sialoprotein expression. | no | no |
title | all | all |