General Information
Gene ID | 8856 |
---|---|
Gene Symbol | NR1I2 |
Gene Name | nuclear receptor subfamily 1, group I, member 2 |
Gene Type | protein-coding |
Cytoband | 3q12-q13.3 |
Ensembl ID | ENSG00000144852 |
#miR regulators | 13 |
Omim ID | 603065 |
Gene ontology |
GO:0007165: signal transduction GO:0006367: transcription initiation from RNA polymerase II promoter GO:0006805: xenobiotic metabolic process GO:0008202: steroid metabolic process GO:0010467: gene expression GO:0045893: positive regulation of transcription, DNA-dependent GO:0045892: negative regulation of transcription, DNA-dependent GO:0030522: intracellular receptor signaling pathway GO:0042738: exogenous drug catabolic process GO:0042908: xenobiotic transport GO:0046618: drug export GO:0005654: nucleoplasm GO:0005515: protein binding GO:0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity GO:0003707: steroid hormone receptor activity GO:0003713: transcription coactivator activity GO:0008144: drug binding GO:0008270: zinc ion binding GO:0043565: sequence-specific DNA binding |
KEGG pathways | --- |
PMID | Title | Tumor | Value |
---|---|---|---|
17279585 | Expression levels and activation of a PXR variant are directly related to drug resistance in osteosarcoma cell lines. | no | no |
18048360 | Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and beta1-integrin on the cell surface. | no | no |
title | all | all |