General Information
| Gene ID | 890 |
|---|---|
| Gene Symbol | CCNA2 |
| Gene Name | cyclin A2 |
| Gene Type | protein-coding |
| Cytoband | 4q27 |
| Ensembl ID | ENSG00000145386 |
| #miR regulators | 3 |
| Omim ID | 123835 |
| Gene ontology |
GO:0000079: regulation of cyclin-dependent protein serine/threonine kinase activity GO:0000086: G2/M transition of mitotic cell cycle GO:0000278: mitotic cell cycle GO:0007067: mitosis GO:0007095: mitotic G2 DNA damage checkpoint GO:0007265: Ras protein signal transduction GO:0045893: positive regulation of transcription, DNA-dependent GO:0051301: cell division GO:0001939: female pronucleus GO:0001940: male pronucleus GO:0005634: nucleus GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0005515: protein binding GO:0019901: protein kinase binding |
| KEGG pathways |
4110: Cell cycle 4914: Progesterone-mediated oocyte maturation |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 1388095 | Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. | no | no |
| 9538120 | Prognostic significance of cyclin expression in human osteosarcoma. | yes | yes |
| 10234573 | ERK pathway mediates the activation of Cdk2 in IGF-1-induced proliferation of human osteosarcoma MG-63 cells. | no | no |
| 14975209 | Effect of human osteopontin on proliferation, transmigration and expression of MMP-2 and MMP-9 in osteosarcoma cells. | no | no |
| 21720717 | Induction of G₂/M arrest and apoptosis by sulforaphane in human osteosarcoma U2-OS cells. | no | no |
| 22231496 | Daphnoretin induces cell cycle arrest and apoptosis in human osteosarcoma (HOS) cells. | no | no |
| 23462806 | Y-box binding protein-1 regulates cell proliferation and is associated with clinical outcomes of osteosarcoma. | no | no |
| title | all | all |