Results for CCNB1

General Information

Gene ID 891
Gene Symbol CCNB1
Gene Name cyclin B1
Gene Type protein-coding
Cytoband 5q12
Ensembl ID ENSG00000134057
#miR regulators 7
Omim ID 123836
Gene ontology GO:0000079: regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082: G1/S transition of mitotic cell cycle
GO:0000086: G2/M transition of mitotic cell cycle
GO:0000236: mitotic prometaphase
GO:0000278: mitotic cell cycle
GO:0001556: oocyte maturation
GO:0001701: in utero embryonic development
GO:0001933: negative regulation of protein phosphorylation
GO:0006461: protein complex assembly
GO:0006468: protein phosphorylation
GO:0009612: response to mechanical stimulus
GO:0007077: mitotic nuclear envelope disassembly
GO:0007080: mitotic metaphase plate congression
GO:0007283: spermatogenesis
GO:0046680: response to DDT
GO:0042493: response to drug
GO:0010629: negative regulation of gene expression
GO:0031145: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031442: positive regulation of mRNA 3'-end processing
GO:0033129: positive regulation of histone phosphorylation
GO:0042246: tissue regeneration
GO:0043148: mitotic spindle stabilization
GO:0045931: positive regulation of mitotic cell cycle
GO:0048565: digestive tract development
GO:0051301: cell division
GO:0051437: positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439: regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051987: positive regulation of attachment of spindle microtubules to kinetochore
GO:0055015: ventricular cardiac muscle cell development
GO:0060045: positive regulation of cardiac muscle cell proliferation
GO:0060623: regulation of chromosome condensation
GO:0071174: mitotic spindle checkpoint
GO:0071283: cellular response to iron(III) ion
GO:0071398: cellular response to fatty acid
GO:0071407: cellular response to organic cyclic compound
GO:0071456: cellular response to hypoxia
GO:0000922: spindle pole
GO:0000942: condensed nuclear chromosome outer kinetochore
GO:0016020: membrane
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005813: centrosome
GO:0005515: protein binding
GO:0005113: patched binding
GO:0016301: kinase activity
GO:0019901: protein kinase binding
KEGG pathways 4110: Cell cycle
4114: Oocyte meiosis
4115: p53 signaling pathway
4914: Progesterone-mediated oocyte maturation

PubMed abstracts associated with CCNB1

PMID Title Tumor Value
8052269 Insulin-like growth factor-I induces cyclin-D1 expression in MG63 human osteosarcoma cells in vitro. no no
16849574 E2F-1 overexpression in U2OS cells increases cyclin B1 levels and cdc2 kinase activity and sensitizes cells to antimitotic agents. no no
17234543 Low-grade central osteosarcoma of the mandible: a case study report. yes no
19559722 Resveratrol induces senescence-like growth inhibition of U-2 OS cells associated with the instability of telomeric DNA and upregulation of BRCA1. no no
20044614 Curcumin induces cell cycle arrest and apoptosis in human osteosarcoma (HOS) cells. no no
20053387 RUNX2 regulates the effects of TNFalpha on proliferation and apoptosis in SaOs-2 cells. no no
21234653 Anti-tumor effects of dihydroartemisinin on human osteosarcoma. no no
21720717 Induction of G₂/M arrest and apoptosis by sulforaphane in human osteosarcoma U2-OS cells. no no
21993662 Plumbagin induces apoptosis via the p53 pathway and generation of reactive oxygen species in human osteosarcoma cells. no no
22231496 Daphnoretin induces cell cycle arrest and apoptosis in human osteosarcoma (HOS) cells. no no
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