Results for WNT3A

General Information

Gene ID 89780
Gene Symbol WNT3A
Gene Name wingless-type MMTV integration site family, member 3A
Gene Type protein-coding
Cytoband 1q42
Ensembl ID ENSG00000154342
#miR regulators 6
Omim ID 606359
Gene ontology GO:0001649: osteoblast differentiation
GO:0001701: in utero embryonic development
GO:0001934: positive regulation of protein phosphorylation
GO:0001947: heart looping
GO:0002092: positive regulation of receptor internalization
GO:0003136: negative regulation of heart induction by canonical Wnt receptor signaling pathway
GO:0007267: cell-cell signaling
GO:0009653: anatomical structure morphogenesis
GO:0007411: axon guidance
GO:0008284: positive regulation of cell proliferation
GO:0010387: COP9 signalosome assembly
GO:0010977: negative regulation of neuron projection development
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0021527: spinal cord association neuron differentiation
GO:0021766: hippocampus development
GO:0021846: cell proliferation in forebrain
GO:0021874: Wnt receptor signaling pathway involved in forebrain neuroblast division
GO:0021904: dorsal/ventral neural tube patterning
GO:0030097: hemopoiesis
GO:0030182: neuron differentiation
GO:0030198: extracellular matrix organization
GO:0030879: mammary gland development
GO:0030890: positive regulation of B cell proliferation
GO:0032092: positive regulation of protein binding
GO:0033138: positive regulation of peptidyl-serine phosphorylation
GO:0034613: cellular protein localization
GO:0036342: post-anal tail morphogenesis
GO:0035413: positive regulation of catenin import into nucleus
GO:0035914: skeletal muscle cell differentiation
GO:0042472: inner ear morphogenesis
GO:0043280: positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045599: negative regulation of fat cell differentiation
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048337: positive regulation of mesodermal cell fate specification
GO:0048343: paraxial mesodermal cell fate commitment
GO:0048697: positive regulation of collateral sprouting in absence of injury
GO:0048843: negative regulation of axon extension involved in axon guidance
GO:0050768: negative regulation of neurogenesis
GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060021: palate development
GO:0060070: canonical Wnt receptor signaling pathway
GO:0061098: positive regulation of protein tyrosine kinase activity
GO:0061184: positive regulation of dermatome development
GO:0061317: canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment
GO:0070507: regulation of microtubule cytoskeleton organization
GO:0070527: platelet aggregation
GO:0071300: cellular response to retinoic acid
GO:0090245: axis elongation involved in somitogenesis
GO:0090263: positive regulation of canonical Wnt receptor signaling pathway
GO:2000049: positive regulation of cell-cell adhesion mediated by cadherin
GO:2000081: positive regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation
GO:2000727: positive regulation of cardiac muscle cell differentiation
GO:0005886: plasma membrane
GO:0005576: extracellular region
GO:0005578: proteinaceous extracellular matrix
GO:0005615: extracellular space
GO:0005788: endoplasmic reticulum lumen
GO:0005796: Golgi lumen
GO:0009986: cell surface
GO:0005515: protein binding
GO:0003713: transcription coactivator activity
GO:0005109: frizzled binding
GO:0005110: frizzled-2 binding
GO:0005201: extracellular matrix structural constituent
GO:0019904: protein domain specific binding
GO:0048018: receptor agonist activity
KEGG pathways 4310: Wnt signaling pathway
4340: Hedgehog signaling pathway
4916: Melanogenesis
5200: Pathways in cancer
5217: Basal cell carcinoma

PubMed abstracts associated with WNT3A

PMID Title Tumor Value
20530678 High Wnt signaling represses the proapoptotic proteoglycan syndecan-2 in osteosarcoma cells. no no
23291185 Inhibition of the Wnt-?-catenin and Notch signaling pathways sensitizes osteosarcoma cells to chemotherapy. yes yes
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