Results for NOG

General Information

Gene ID 9241
Gene Symbol NOG
Gene Name noggin
Gene Type protein-coding
Cytoband 17q22
Ensembl ID ENSG00000183691
#miR regulators 5
Omim ID 184460 185800 186500 186570 602991 611377
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001501: skeletal system development
GO:0001649: osteoblast differentiation
GO:0001701: in utero embryonic development
GO:0001706: endoderm formation
GO:0001707: mesoderm formation
GO:0001837: epithelial to mesenchymal transition
GO:0001839: neural plate morphogenesis
GO:0001843: neural tube closure
GO:0007399: nervous system development
GO:0008045: motor neuron axon guidance
GO:0043066: negative regulation of apoptotic process
GO:0009953: dorsal/ventral pattern formation
GO:0021510: spinal cord development
GO:0021533: cell differentiation in hindbrain
GO:0021983: pituitary gland development
GO:0030336: negative regulation of cell migration
GO:0030509: BMP signaling pathway
GO:0030514: negative regulation of BMP signaling pathway
GO:0035019: somatic stem cell maintenance
GO:0042060: wound healing
GO:0042474: middle ear morphogenesis
GO:0042733: embryonic digit morphogenesis
GO:0045668: negative regulation of osteoblast differentiation
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048318: axial mesoderm development
GO:0048570: notochord morphogenesis
GO:0048706: embryonic skeletal system development
GO:0048712: negative regulation of astrocyte differentiation
GO:0050679: positive regulation of epithelial cell proliferation
GO:0051216: cartilage development
GO:0060044: negative regulation of cardiac muscle cell proliferation
GO:0060173: limb development
GO:0060272: embryonic skeletal joint morphogenesis
GO:0060302: negative regulation of cytokine activity
GO:0060325: face morphogenesis
GO:0060394: negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0060425: lung morphogenesis
GO:0060513: prostatic bud formation
GO:0060676: ureteric bud formation
GO:0060825: fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
GO:0061037: negative regulation of cartilage development
GO:0061053: somite development
GO:0071773: cellular response to BMP stimulus
GO:0090090: negative regulation of canonical Wnt receptor signaling pathway
GO:0090190: positive regulation of branching involved in ureteric bud morphogenesis
GO:0090193: positive regulation of glomerulus development
GO:2000313: regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
GO:0005576: extracellular region
GO:0005615: extracellular space
GO:0019955: cytokine binding
GO:0042803: protein homodimerization activity
KEGG pathways 4350: TGF-beta signaling pathway

PubMed abstracts associated with NOG

PMID Title Tumor Value
16470222 RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation. no no
19142873 De-sulfation of MG-63 cell glycosaminoglycans delays in vitro osteogenesis, up-regulates cholesterol synthesis and disrupts cell cycle and the actin cytoskeleton. no no
title all all