General Information
Gene ID | 9241 |
---|---|
Gene Symbol | NOG |
Gene Name | noggin |
Gene Type | protein-coding |
Cytoband | 17q22 |
Ensembl ID | ENSG00000183691 |
#miR regulators | 5 |
Omim ID | 184460 185800 186500 186570 602991 611377 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0001501: skeletal system development GO:0001649: osteoblast differentiation GO:0001701: in utero embryonic development GO:0001706: endoderm formation GO:0001707: mesoderm formation GO:0001837: epithelial to mesenchymal transition GO:0001839: neural plate morphogenesis GO:0001843: neural tube closure GO:0007399: nervous system development GO:0008045: motor neuron axon guidance GO:0043066: negative regulation of apoptotic process GO:0009953: dorsal/ventral pattern formation GO:0021510: spinal cord development GO:0021533: cell differentiation in hindbrain GO:0021983: pituitary gland development GO:0030336: negative regulation of cell migration GO:0030509: BMP signaling pathway GO:0030514: negative regulation of BMP signaling pathway GO:0035019: somatic stem cell maintenance GO:0042060: wound healing GO:0042474: middle ear morphogenesis GO:0042733: embryonic digit morphogenesis GO:0045668: negative regulation of osteoblast differentiation GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0048318: axial mesoderm development GO:0048570: notochord morphogenesis GO:0048706: embryonic skeletal system development GO:0048712: negative regulation of astrocyte differentiation GO:0050679: positive regulation of epithelial cell proliferation GO:0051216: cartilage development GO:0060044: negative regulation of cardiac muscle cell proliferation GO:0060173: limb development GO:0060272: embryonic skeletal joint morphogenesis GO:0060302: negative regulation of cytokine activity GO:0060325: face morphogenesis GO:0060394: negative regulation of pathway-restricted SMAD protein phosphorylation GO:0060425: lung morphogenesis GO:0060513: prostatic bud formation GO:0060676: ureteric bud formation GO:0060825: fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation GO:0061037: negative regulation of cartilage development GO:0061053: somite development GO:0071773: cellular response to BMP stimulus GO:0090090: negative regulation of canonical Wnt receptor signaling pathway GO:0090190: positive regulation of branching involved in ureteric bud morphogenesis GO:0090193: positive regulation of glomerulus development GO:2000313: regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation GO:0005576: extracellular region GO:0005615: extracellular space GO:0019955: cytokine binding GO:0042803: protein homodimerization activity |
KEGG pathways |
4350: TGF-beta signaling pathway |
PMID | Title | Tumor | Value |
---|---|---|---|
16470222 | RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation. | no | no |
19142873 | De-sulfation of MG-63 cell glycosaminoglycans delays in vitro osteogenesis, up-regulates cholesterol synthesis and disrupts cell cycle and the actin cytoskeleton. | no | no |
title | all | all |