Results for ABCG2

General Information

Gene ID 9429
Gene Symbol ABCG2
Gene Name ATP-binding cassette, sub-family G (WHITE), member 2
Gene Type protein-coding
Cytoband 4q22
Ensembl ID ENSG00000118777
#miR regulators 14
Omim ID 138900 603756 614490
Gene ontology GO:0006810: transport
GO:0006855: drug transmembrane transport
GO:0006879: cellular iron ion homeostasis
GO:0042493: response to drug
GO:0015886: heme transport
GO:0044281: small molecule metabolic process
GO:0046415: urate metabolic process
GO:0055085: transmembrane transport
GO:0005886: plasma membrane
GO:0016021: integral to membrane
GO:0005515: protein binding
GO:0042626: ATPase activity, coupled to transmembrane movement of substances
GO:0005215: transporter activity
GO:0005524: ATP binding
GO:0008559: xenobiotic-transporting ATPase activity
GO:0015232: heme transporter activity
GO:0042803: protein homodimerization activity
KEGG pathways 2010: ABC transporters
4976: Bile secretion

PubMed abstracts associated with ABCG2

PMID Title Tumor Value
15138564 Differentially expressed genes in multidrug resistant variants of U-2 OS human osteosarcoma cells. no no
17045162 Multidrug resistance mediated by ABC transporters in osteosarcoma cell lines: mRNA analysis and functional radiotracer studies. no no
18507006 Identification of potential chemoresistance genes in osteosarcoma. no no
18941626 Detection and characterization of CD133+ cancer stem cells in human solid tumours. no no
19160414 Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment. no no
20460510 CD117 and Stro-1 identify osteosarcoma tumor-initiating cells associated with metastasis and drug resistance. no no
22870217 Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma. no no
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