General Information
| Gene ID | 9429 |
|---|---|
| Gene Symbol | ABCG2 |
| Gene Name | ATP-binding cassette, sub-family G (WHITE), member 2 |
| Gene Type | protein-coding |
| Cytoband | 4q22 |
| Ensembl ID | ENSG00000118777 |
| #miR regulators | 14 |
| Omim ID | 138900 603756 614490 |
| Gene ontology |
GO:0006810: transport GO:0006855: drug transmembrane transport GO:0006879: cellular iron ion homeostasis GO:0042493: response to drug GO:0015886: heme transport GO:0044281: small molecule metabolic process GO:0046415: urate metabolic process GO:0055085: transmembrane transport GO:0005886: plasma membrane GO:0016021: integral to membrane GO:0005515: protein binding GO:0042626: ATPase activity, coupled to transmembrane movement of substances GO:0005215: transporter activity GO:0005524: ATP binding GO:0008559: xenobiotic-transporting ATPase activity GO:0015232: heme transporter activity GO:0042803: protein homodimerization activity |
| KEGG pathways |
2010: ABC transporters 4976: Bile secretion |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 15138564 | Differentially expressed genes in multidrug resistant variants of U-2 OS human osteosarcoma cells. | no | no |
| 17045162 | Multidrug resistance mediated by ABC transporters in osteosarcoma cell lines: mRNA analysis and functional radiotracer studies. | no | no |
| 18507006 | Identification of potential chemoresistance genes in osteosarcoma. | no | no |
| 18941626 | Detection and characterization of CD133+ cancer stem cells in human solid tumours. | no | no |
| 19160414 | Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment. | no | no |
| 20460510 | CD117 and Stro-1 identify osteosarcoma tumor-initiating cells associated with metastasis and drug resistance. | no | no |
| 22870217 | Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma. | no | no |
| title | all | all |