Results for HDAC4

General Information

Gene ID 9759
Gene Symbol HDAC4
Gene Name histone deacetylase 4
Gene Type protein-coding
Cytoband 2q37.3
Ensembl ID ENSG00000068024
#miR regulators 7
Omim ID 600430 605314
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001501: skeletal system development
GO:0002076: osteoblast development
GO:0006338: chromatin remodeling
GO:0006351: transcription, DNA-dependent
GO:0006954: inflammatory response
GO:0007399: nervous system development
GO:0008284: positive regulation of cell proliferation
GO:0008285: negative regulation of cell proliferation
GO:0042493: response to drug
GO:0010832: negative regulation of myotube differentiation
GO:0010882: regulation of cardiac muscle contraction by calcium ion signaling
GO:0014894: response to denervation involved in regulation of muscle adaptation
GO:0014898: cardiac muscle hypertrophy in response to stress
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0016575: histone deacetylation
GO:0030183: B cell differentiation
GO:0033235: positive regulation of protein sumoylation
GO:0034983: peptidyl-lysine deacetylation
GO:0042113: B cell activation
GO:0043393: regulation of protein binding
GO:0043433: negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045668: negative regulation of osteoblast differentiation
GO:0045820: negative regulation of glycolysis
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070555: response to interleukin-1
GO:0070932: histone H3 deacetylation
GO:0070933: histone H4 deacetylation
GO:0000118: histone deacetylase complex
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0017053: transcriptional repressor complex
GO:0030018: Z disc
GO:0031594: neuromuscular junction
GO:0031672: A band
GO:0042641: actomyosin
GO:0005515: protein binding
GO:0003714: transcription corepressor activity
GO:0004407: histone deacetylase activity
GO:0008134: transcription factor binding
GO:0008270: zinc ion binding
GO:0044212: transcription regulatory region DNA binding
GO:0019901: protein kinase binding
GO:0030955: potassium ion binding
GO:0032041: NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0033558: protein deacetylase activity
GO:0033613: activating transcription factor binding
GO:0042826: histone deacetylase binding
GO:0043565: sequence-specific DNA binding
GO:0046969: NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970: NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0070491: repressing transcription factor binding
GO:0097372: NAD-dependent histone deacetylase activity (H3-K18 specific)
KEGG pathways ---

PubMed abstracts associated with HDAC4

PMID Title Tumor Value
19734943 Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells. no no
title all all