Results for CDH1

General Information

Gene ID 999
Gene Symbol CDH1
Gene Name cadherin 1, type 1, E-cadherin (epithelial)
Gene Type protein-coding
Cytoband 16q22.1
Ensembl ID ENSG00000039068
#miR regulators 7
Omim ID 114480 137215 176807 192090 608089
Gene ontology GO:0001829: trophectodermal cell differentiation
GO:0006915: apoptotic process
GO:0006921: cellular component disassembly involved in execution phase of apoptosis
GO:0007156: homophilic cell adhesion
GO:0007416: synapse assembly
GO:0007605: sensory perception of sound
GO:0042493: response to drug
GO:0009636: response to toxic substance
GO:0016337: cell-cell adhesion
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0019538: protein metabolic process
GO:0021983: pituitary gland development
GO:0022408: negative regulation of cell-cell adhesion
GO:0071230: cellular response to amino acid stimulus
GO:0031175: neuron projection development
GO:0033561: regulation of water loss via skin
GO:0034329: cell junction assembly
GO:0034332: adherens junction organization
GO:0051260: protein homooligomerization
GO:0042993: positive regulation of transcription factor import into nucleus
GO:0043281: regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045216: cell-cell junction organization
GO:0050776: regulation of immune response
GO:0060662: salivary gland cavitation
GO:0060693: regulation of branching involved in salivary gland morphogenesis
GO:0070830: tight junction assembly
GO:0071285: cellular response to lithium ion
GO:0071681: cellular response to indole-3-methanol
GO:0072659: protein localization to plasma membrane
GO:0090102: cochlea development
GO:2000008: regulation of protein localization to cell surface
GO:0005886: plasma membrane
GO:0016021: integral to membrane
GO:0005737: cytoplasm
GO:0005768: endosome
GO:0005794: Golgi apparatus
GO:0005802: trans-Golgi network
GO:0005913: cell-cell adherens junction
GO:0005925: focal adhesion
GO:0009898: internal side of plasma membrane
GO:0009986: cell surface
GO:0015629: actin cytoskeleton
GO:0016235: aggresome
GO:0016323: basolateral plasma membrane
GO:0016328: lateral plasma membrane
GO:0016342: catenin complex
GO:0030054: cell junction
GO:0033268: node of Ranvier
GO:0043219: lateral loop
GO:0043220: Schmidt-Lanterman incisure
GO:0043296: apical junction complex
GO:0043679: axon terminus
GO:0045177: apical part of cell
GO:0048471: perinuclear region of cytoplasm
GO:0005515: protein binding
GO:0005509: calcium ion binding
GO:0050839: cell adhesion molecule binding
GO:0008013: beta-catenin binding
GO:0019903: protein phosphatase binding
GO:0019904: protein domain specific binding
GO:0030506: ankyrin binding
GO:0032794: GTPase activating protein binding
GO:0045295: gamma-catenin binding
KEGG pathways 4514: Cell adhesion molecules (CAMs)
4520: Adherens junction
5100: Bacterial invasion of epithelial cells
5130: Pathogenic Escherichia coli infection
5200: Pathways in cancer
5213: Endometrial cancer
5216: Thyroid cancer
5218: Melanoma
5219: Bladder cancer

PubMed abstracts associated with CDH1

PMID Title Tumor Value
17318900 Blocking Wnt/LRP5 signaling by a soluble receptor modulates the epithelial to mesenchymal transition and suppresses met and metalloproteinases in osteosarcoma Saos-2 cells. no no
20978190 Silencing of autocrine motility factor induces mesenchymal-to-epithelial transition and suppression of osteosarcoma pulmonary metastasis. no no
22006429 High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes. yes no
22546756 Cyclooxygenase-2 inhibitors induce anoikis in osteosarcoma via PI3K/Akt pathway. no no
22847601 Prognostic value of Twist and E-cadherin in patients with osteosarcoma. yes yes
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