General Information
Gene ID | 999 |
---|---|
Gene Symbol | CDH1 |
Gene Name | cadherin 1, type 1, E-cadherin (epithelial) |
Gene Type | protein-coding |
Cytoband | 16q22.1 |
Ensembl ID | ENSG00000039068 |
#miR regulators | 7 |
Omim ID | 114480 137215 176807 192090 608089 |
Gene ontology |
GO:0001829: trophectodermal cell differentiation GO:0006915: apoptotic process GO:0006921: cellular component disassembly involved in execution phase of apoptosis GO:0007156: homophilic cell adhesion GO:0007416: synapse assembly GO:0007605: sensory perception of sound GO:0042493: response to drug GO:0009636: response to toxic substance GO:0016337: cell-cell adhesion GO:0045893: positive regulation of transcription, DNA-dependent GO:0019538: protein metabolic process GO:0021983: pituitary gland development GO:0022408: negative regulation of cell-cell adhesion GO:0071230: cellular response to amino acid stimulus GO:0031175: neuron projection development GO:0033561: regulation of water loss via skin GO:0034329: cell junction assembly GO:0034332: adherens junction organization GO:0051260: protein homooligomerization GO:0042993: positive regulation of transcription factor import into nucleus GO:0043281: regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0045216: cell-cell junction organization GO:0050776: regulation of immune response GO:0060662: salivary gland cavitation GO:0060693: regulation of branching involved in salivary gland morphogenesis GO:0070830: tight junction assembly GO:0071285: cellular response to lithium ion GO:0071681: cellular response to indole-3-methanol GO:0072659: protein localization to plasma membrane GO:0090102: cochlea development GO:2000008: regulation of protein localization to cell surface GO:0005886: plasma membrane GO:0016021: integral to membrane GO:0005737: cytoplasm GO:0005768: endosome GO:0005794: Golgi apparatus GO:0005802: trans-Golgi network GO:0005913: cell-cell adherens junction GO:0005925: focal adhesion GO:0009898: internal side of plasma membrane GO:0009986: cell surface GO:0015629: actin cytoskeleton GO:0016235: aggresome GO:0016323: basolateral plasma membrane GO:0016328: lateral plasma membrane GO:0016342: catenin complex GO:0030054: cell junction GO:0033268: node of Ranvier GO:0043219: lateral loop GO:0043220: Schmidt-Lanterman incisure GO:0043296: apical junction complex GO:0043679: axon terminus GO:0045177: apical part of cell GO:0048471: perinuclear region of cytoplasm GO:0005515: protein binding GO:0005509: calcium ion binding GO:0050839: cell adhesion molecule binding GO:0008013: beta-catenin binding GO:0019903: protein phosphatase binding GO:0019904: protein domain specific binding GO:0030506: ankyrin binding GO:0032794: GTPase activating protein binding GO:0045295: gamma-catenin binding |
KEGG pathways |
4514: Cell adhesion molecules (CAMs) 4520: Adherens junction 5100: Bacterial invasion of epithelial cells 5130: Pathogenic Escherichia coli infection 5200: Pathways in cancer 5213: Endometrial cancer 5216: Thyroid cancer 5218: Melanoma 5219: Bladder cancer |
PMID | Title | Tumor | Value |
---|---|---|---|
17318900 | Blocking Wnt/LRP5 signaling by a soluble receptor modulates the epithelial to mesenchymal transition and suppresses met and metalloproteinases in osteosarcoma Saos-2 cells. | no | no |
20978190 | Silencing of autocrine motility factor induces mesenchymal-to-epithelial transition and suppression of osteosarcoma pulmonary metastasis. | no | no |
22006429 | High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes. | yes | no |
22546756 | Cyclooxygenase-2 inhibitors induce anoikis in osteosarcoma via PI3K/Akt pathway. | no | no |
22847601 | Prognostic value of Twist and E-cadherin in patients with osteosarcoma. | yes | yes |
title | all | all |